Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification

Toshifumi Miyazawa; Kazuki Onishi; Takashi Murashima; Takashi Yamada; Shau Wei Tsai

doi:10.1016/j.tetasy.2005.06.037

Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification

Toshifumi Miyazawa^*
, Kazuki Onishi
, Takashi Murashima
, Takashi Yamada
, Shau Wei Tsai

^*Corresponding author for this work

Konan University
National Cheng Kung University

Research output: Contribution to journal › Journal Article › peer-review

19 Scopus citations

Abstract

Carica papaya lipase-catalyzed transesterification of the 2,2,2-trifluoroethyl esters of N-benzyloxycarbonylated dl-amino acids carrying aliphatic side chains proceeded smoothly and, in almost all the cases, enantiospecifically (E = >200), affording the l-methyl esters and leaving the d-trifluoroethyl esters intact.

Original language	English
Pages (from-to)	2569-2573
Number of pages	5
Journal	Tetrahedron Asymmetry
Volume	16
Issue number	15
DOIs	https://doi.org/10.1016/j.tetasy.2005.06.037
State	Published - 01 08 2005
Externally published	Yes

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10.1016/j.tetasy.2005.06.037

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title = "Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification",

abstract = "Carica papaya lipase-catalyzed transesterification of the 2,2,2-trifluoroethyl esters of N-benzyloxycarbonylated dl-amino acids carrying aliphatic side chains proceeded smoothly and, in almost all the cases, enantiospecifically (E = >200), affording the l-methyl esters and leaving the d-trifluoroethyl esters intact.",

author = "Toshifumi Miyazawa and Kazuki Onishi and Takashi Murashima and Takashi Yamada and Tsai, \{Shau Wei\}",

year = "2005",

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T1 - Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification

AU - Miyazawa, Toshifumi

AU - Onishi, Kazuki

AU - Murashima, Takashi

AU - Yamada, Takashi

AU - Tsai, Shau Wei

PY - 2005/8/1

Y1 - 2005/8/1

N2 - Carica papaya lipase-catalyzed transesterification of the 2,2,2-trifluoroethyl esters of N-benzyloxycarbonylated dl-amino acids carrying aliphatic side chains proceeded smoothly and, in almost all the cases, enantiospecifically (E = >200), affording the l-methyl esters and leaving the d-trifluoroethyl esters intact.

AB - Carica papaya lipase-catalyzed transesterification of the 2,2,2-trifluoroethyl esters of N-benzyloxycarbonylated dl-amino acids carrying aliphatic side chains proceeded smoothly and, in almost all the cases, enantiospecifically (E = >200), affording the l-methyl esters and leaving the d-trifluoroethyl esters intact.

UR - https://www.scopus.com/pages/publications/23644454974

U2 - 10.1016/j.tetasy.2005.06.037

DO - 10.1016/j.tetasy.2005.06.037

M3 - 文章

AN - SCOPUS:23644454974

SN - 0957-4166

VL - 16

SP - 2569

EP - 2573

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

IS - 15

ER -

Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification

Abstract

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