Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices

Nai Shin Chu; Larry Keenan

doi:10.1016/0741-8329(87)90069-3

Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices

Nai Shin Chu^*
, Larry Keenan

^*Corresponding author for this work

University of California at Irvine

Research output: Contribution to journal › Journal Article › peer-review

18 Scopus citations

Abstract

The effects of ethanol on midbrain dorsal raphe (DR) neurons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg% and 200 mg%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.

Original language	English
Pages (from-to)	373-374
Number of pages	2
Journal	Alcohol
Volume	4
Issue number	5
DOIs	https://doi.org/10.1016/0741-8329(87)90069-3
State	Published - 1987
Externally published	Yes

Keywords

Brain slice
Dorsal raphe neurons
Ethanol

Access to Document

10.1016/0741-8329(87)90069-3

Cite this

@article{c3c8956a063d45519d43d7b63f8e8308,

title = "Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices",

abstract = "The effects of ethanol on midbrain dorsal raphe (DR) neurons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg\% and 200 mg\%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.",

keywords = "Brain slice, Dorsal raphe neurons, Ethanol",

author = "Chu, \{Nai Shin\} and Larry Keenan",

year = "1987",

doi = "10.1016/0741-8329(87)90069-3",

language = "英语",

volume = "4",

pages = "373--374",

journal = "Alcohol",

issn = "0741-8329",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices

AU - Chu, Nai Shin

AU - Keenan, Larry

PY - 1987

Y1 - 1987

N2 - The effects of ethanol on midbrain dorsal raphe (DR) neurons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg% and 200 mg%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.

AB - The effects of ethanol on midbrain dorsal raphe (DR) neurons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg% and 200 mg%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.

KW - Brain slice

KW - Dorsal raphe neurons

KW - Ethanol

UR - https://www.scopus.com/pages/publications/0023407002

U2 - 10.1016/0741-8329(87)90069-3

DO - 10.1016/0741-8329(87)90069-3

M3 - 文章

C2 - 3675858

AN - SCOPUS:0023407002

SN - 0741-8329

VL - 4

SP - 373

EP - 374

JO - Alcohol

JF - Alcohol

IS - 5

ER -

Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this