Abstract
We report a case of polycythemia vera with chorea in which the brain metabolism and dopamine system were investigated using 2-[ 18F]fluoro- 2-deoxy-D-glucose positron emission tomography (FDG PET) and 99mTc-labeled tropane dopamine transporter ( 99mTc-TRODAT- 1) single photon emission computed tomography (SPECT). Along with normalization of the hematocrit and clinical symptoms after consecutive phlebotomies, the FDG PET scan and 99mTc-TRODAT-1 SPECT images returned towards normal. It is hypothesized that the development of polycythemia chorea is associated with a reversible alteration in the corticobasal ganglia metabolism and disturbed dopaminergic function.
Original language | English |
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Pages (from-to) | 2054-2057 |
Number of pages | 4 |
Journal | Journal of Neurology |
Volume | 258 |
Issue number | 11 |
DOIs | |
State | Published - 11 2011 |
Externally published | Yes |
Keywords
- Chorea
- PET
- Polycythemia vera
- Tc-TRODAT-1