Reversible abnormal functional neuroimaging presentations in polycythemia vera with chorea

Hui Chun Huang, Yu Chin Wu, Lee Yung Shih, Woei Chung Lo, Chon Haw Tsai*, Woei Cherng Shyu

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

15 Scopus citations

Abstract

We report a case of polycythemia vera with chorea in which the brain metabolism and dopamine system were investigated using 2-[ 18F]fluoro- 2-deoxy-D-glucose positron emission tomography (FDG PET) and 99mTc-labeled tropane dopamine transporter ( 99mTc-TRODAT- 1) single photon emission computed tomography (SPECT). Along with normalization of the hematocrit and clinical symptoms after consecutive phlebotomies, the FDG PET scan and 99mTc-TRODAT-1 SPECT images returned towards normal. It is hypothesized that the development of polycythemia chorea is associated with a reversible alteration in the corticobasal ganglia metabolism and disturbed dopaminergic function.

Original languageEnglish
Pages (from-to)2054-2057
Number of pages4
JournalJournal of Neurology
Volume258
Issue number11
DOIs
StatePublished - 11 2011
Externally publishedYes

Keywords

  • Chorea
  • PET
  • Polycythemia vera
  • Tc-TRODAT-1

Fingerprint

Dive into the research topics of 'Reversible abnormal functional neuroimaging presentations in polycythemia vera with chorea'. Together they form a unique fingerprint.

Cite this