Rhabdomyolysis, acute renal failure and hepatopathy induced by lovastatin monotherapy

Pao-Hsien Chu*, Wei Jan Chen, Cheng-Wen Chiang, Ying-Shiung Lee

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

17 Scopus citations

Abstract

Lovastatin is a popular drug for the treatment of hypercholesterolemia. Few serious complications are associated with its use although rhabdomyolysis with renal failure has been reported when lovastatin is combined with cyclosporine or other drugs following transplantation. We report the case of a patient who developed hepatopathy and rhabdomyolysis accompanied by acute renal failure after 4 weeks of lovastatin monotherapy. The pathogenesis and treatment of these complications are also discussed.

Original languageEnglish
Pages (from-to)541-545
Number of pages5
JournalJapanese Heart Journal
Volume38
Issue number4
DOIs
StatePublished - 07 1997
Externally publishedYes

Keywords

  • Acute renal failure
  • Lovastatin
  • Rhabdomyolysis

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