Risk factors and perinatal outcomes associated with idiopathic small for gestational age Taiwanese newborns

Tai Ho Hung*, T'Sang T.Ang Hsieh, Liang Ming Lo, Tsung Hung Chiu, Ching Chang Hsieh, Jenn Jeih Hsu

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

10 Scopus citations

Abstract

Objective To determine risk factors and perinatal outcomes associated with small for gestational age (SGA) neonates among healthy pregnant women. Methods A retrospective cohort study was conducted of 49 945 women who gave birth at Chang Gung Memorial Hospital, Taipei, Taiwan, after 24 weeks of pregnancy. Idiopathic SGA newborns (n = 3398) were characterized by a birth weight below the 10th percentile for mean weight corrected for GA and fetal sex. Results Risk factors for idiopathic SGA newborns included hypercoiling of the umbilical cord (adjusted odds ratio [aOR], 3.3; 95% confidence interval [CI], 1.6-7.0); prior fetal death (aOR, 2.8; 95% CI, 2.0-3.9); primiparity (aOR, 1.5; 95% CI, 1.4-1.7); adolescent pregnancy (aOR, 1.5; 95% CI, 1.2-2.0), low prepregnancy weight (aOR, 1.6; 95% CI, 1.5-1.8), low prepregnancy body mass index (aOR, 1.1; 95% CI, 1.0-1.3); short stature (aOR, 1.3; 95% CI, 1.1-1.4); and entangled umbilical cord (aOR, 1.1; 95% CI, 1.0-1.3). Idiopathic SGA newborns correlated with increased risk of adverse perinatal outcomes, including fetal death, low Apgar scores, oligohydramnios, placental abruption, and admission to the neonatal intensive care unit. Conclusion Some risk factors for idiopathic SGA newborns were modifiable, suggesting potential implications for public health.

Original languageEnglish
Pages (from-to)212-215
Number of pages4
JournalInternational Journal of Gynecology and Obstetrics
Volume122
Issue number3
DOIs
StatePublished - 09 2013

Keywords

  • Body mass index
  • Fetal growth restriction
  • Pregnancy
  • Risk factor
  • Small for gestational age

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