TY - JOUR
T1 - Risk factors associated with hepatitis C virus infection in Taiwanese government employees
AU - Chang, H. C.
AU - Yu, M. W.
AU - Lu, C. F.
AU - Chiu, Y. H.
AU - Chen, C. J.
PY - 2001/4
Y1 - 2001/4
N2 - This study evaluated the roles of multiple factors in hepatitis C virus (HCV) infection, with emphasis on the modification of various individual characteristics on the risk associated with percutaneous exposure to blood. Serum samples taken from 4869 men in Taiwan within a cohort study were tested for HCV antibody. The overall positive rate of anti-HCV was 1.6%. In a logistic regression, factors positively associated with anti-HCV positivity were previous blood transfusion (odds ratio [OR] = 7.28; 95% confidence interval [CI] = 4.26-12.45), a history of surgery (OR = 2.06; 95% CI = 1.23-3.46), and lower educational levels (OR = 1.94; 95% CI = 1.14-3.32). The anti-HCV positive rate was significantly lower in hepatitis B surface antigen (HBsAg) carriers than in non-carriers (OR = 0.60; 95% CI = 0.37-0.95). Ageing, lower educational levels, O blood group, and Taiwanese ethnicity enhanced the likelihood of HCV infection through blood transfusion/surgery, whereas HBsAg status, cigarette smoking, and habitual alcohol drinking reduced it.
AB - This study evaluated the roles of multiple factors in hepatitis C virus (HCV) infection, with emphasis on the modification of various individual characteristics on the risk associated with percutaneous exposure to blood. Serum samples taken from 4869 men in Taiwan within a cohort study were tested for HCV antibody. The overall positive rate of anti-HCV was 1.6%. In a logistic regression, factors positively associated with anti-HCV positivity were previous blood transfusion (odds ratio [OR] = 7.28; 95% confidence interval [CI] = 4.26-12.45), a history of surgery (OR = 2.06; 95% CI = 1.23-3.46), and lower educational levels (OR = 1.94; 95% CI = 1.14-3.32). The anti-HCV positive rate was significantly lower in hepatitis B surface antigen (HBsAg) carriers than in non-carriers (OR = 0.60; 95% CI = 0.37-0.95). Ageing, lower educational levels, O blood group, and Taiwanese ethnicity enhanced the likelihood of HCV infection through blood transfusion/surgery, whereas HBsAg status, cigarette smoking, and habitual alcohol drinking reduced it.
UR - http://www.scopus.com/inward/record.url?scp=0035018053&partnerID=8YFLogxK
U2 - 10.1017/S0950268801005362
DO - 10.1017/S0950268801005362
M3 - 文章
C2 - 11349980
AN - SCOPUS:0035018053
SN - 0950-2688
VL - 126
SP - 291
EP - 299
JO - Epidemiology and Infection
JF - Epidemiology and Infection
IS - 2
ER -
