Risk factors for alzheimer’s disease: A case-control study

Pei Ning Wang; Shuu Jiun Wang; Chen Jee Hong; Tsung Tun Liu; Jong Ling Fuh; Chin Wen Chi; Chia Yih Liu; Hsiu Chih Liu

doi:10.1159/000109692

Risk factors for alzheimer’s disease: A case-control study

Pei Ning Wang
, Shuu Jiun Wang
, Chen Jee Hong
, Tsung Tun Liu
, Jong Ling Fuh
, Chin Wen Chi
, Chia Yih Liu
, Hsiu Chih Liu^*

^*Corresponding author for this work

School of Medicine

Research output: Contribution to journal › Journal Article › peer-review

30 Scopus citations

Abstract

The extent of current knowledge of risk factors for Alzheimer’s disease (AD) is still limited. We conducted a case-control study of 98 AD patients and 98 age- and sex-matched controls. Light smoking had a decreased risk for AD (AD: 2.0%, controls: 21.4%, odds ratio = 0.10, p = 0.003), whereas daily smoking showed a trend to increase the risk for AD (AD: 45.9%, controls: 26.5%, odds ratio = 1.73, p = 0.08). After multivariable analyses factors associated with AD included the presence of apolipoprotein ε4 allele, and the duration of well water consumption.

Original language	English
Pages (from-to)	234-240
Number of pages	7
Journal	Neuroepidemiology
Volume	16
Issue number	5
DOIs	https://doi.org/10.1159/000109692
State	Published - 1997

Keywords

Alzheimer’s disease
Apolipoprotein E
Risk factors
Smoking
Well water

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10.1159/000109692

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title = "Risk factors for alzheimer{\textquoteright}s disease: A case-control study",

abstract = "The extent of current knowledge of risk factors for Alzheimer{\textquoteright}s disease (AD) is still limited. We conducted a case-control study of 98 AD patients and 98 age- and sex-matched controls. Light smoking had a decreased risk for AD (AD: 2.0\%, controls: 21.4\%, odds ratio = 0.10, p = 0.003), whereas daily smoking showed a trend to increase the risk for AD (AD: 45.9\%, controls: 26.5\%, odds ratio = 1.73, p = 0.08). After multivariable analyses factors associated with AD included the presence of apolipoprotein ε4 allele, and the duration of well water consumption.",

keywords = "Alzheimer\’s disease, Apolipoprotein E, Risk factors, Smoking, Well water",

author = "Wang, \{Pei Ning\} and Wang, \{Shuu Jiun\} and Hong, \{Chen Jee\} and Liu, \{Tsung Tun\} and Fuh, \{Jong Ling\} and Chi, \{Chin Wen\} and Liu, \{Chia Yih\} and Liu, \{Hsiu Chih\}",

year = "1997",

doi = "10.1159/000109692",

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T1 - Risk factors for alzheimer’s disease

T2 - A case-control study

AU - Wang, Pei Ning

AU - Wang, Shuu Jiun

AU - Hong, Chen Jee

AU - Liu, Tsung Tun

AU - Fuh, Jong Ling

AU - Chi, Chin Wen

AU - Liu, Chia Yih

AU - Liu, Hsiu Chih

PY - 1997

Y1 - 1997

N2 - The extent of current knowledge of risk factors for Alzheimer’s disease (AD) is still limited. We conducted a case-control study of 98 AD patients and 98 age- and sex-matched controls. Light smoking had a decreased risk for AD (AD: 2.0%, controls: 21.4%, odds ratio = 0.10, p = 0.003), whereas daily smoking showed a trend to increase the risk for AD (AD: 45.9%, controls: 26.5%, odds ratio = 1.73, p = 0.08). After multivariable analyses factors associated with AD included the presence of apolipoprotein ε4 allele, and the duration of well water consumption.

AB - The extent of current knowledge of risk factors for Alzheimer’s disease (AD) is still limited. We conducted a case-control study of 98 AD patients and 98 age- and sex-matched controls. Light smoking had a decreased risk for AD (AD: 2.0%, controls: 21.4%, odds ratio = 0.10, p = 0.003), whereas daily smoking showed a trend to increase the risk for AD (AD: 45.9%, controls: 26.5%, odds ratio = 1.73, p = 0.08). After multivariable analyses factors associated with AD included the presence of apolipoprotein ε4 allele, and the duration of well water consumption.

KW - Alzheimer’s disease

KW - Apolipoprotein E

KW - Risk factors

KW - Smoking

KW - Well water

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DO - 10.1159/000109692

M3 - 文章

C2 - 9346343

AN - SCOPUS:0030882167

SN - 0251-5350

VL - 16

SP - 234

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JO - Neuroepidemiology

JF - Neuroepidemiology

IS - 5

ER -

Risk factors for alzheimer’s disease: A case-control study

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Keywords

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