Risk factors for intestinal gangrene in children with small-bowel volvulus

Yu Pi Lin, Jung Lee, Hsun Chin Chao*, Man Shan Kong, Ming Wei Lai, Chien Chang Chen, Shih Yen Chen, Chih Cheng Luo

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

13 Scopus citations

Abstract

Objectives: Pediatric small-bowel volvulus (SBV) is a surgical emergency, and early diagnosis is difficult. We analyzed the clinical manifestations, imaging findings, and laboratory parameters in children with SBV and attempted to determine the risk factors for bowel gangrene. Patients and Methods: Forty-nine children (35 boys and 14 girls) with SBV who were admitted to the hospital for a period of 13 years were enrolled. Clinical and laboratory parameters and evaluation measures included fever, abdominal pain, vomiting, bloody stool, peritoneal signs, severe dehydration, disease duration, white blood cell counts, sugar, C-reactive protein (CRP), sodium, potassium, metabolic acidosis, blood urea nitrogen, and creatinine. These parameters were statistically compared between patients with and without bowel gangrene. Results: Thirty-six patients (73.5%) were 5 years old or younger, and nearly half were younger than 1 year old. Abdominal pain and vomiting were 2 major symptoms. Malrotation was the most common cause of SBV. In univariate analysis, nonbilious vomiting, peritoneal signs, severe dehydration, leukocytosis (WBC count >18,000cells/mm), elevated CRP (>50mg/dL), and hyponatremia (<130mmol/L) were significantly associated with bowel gangrene (P<0.05). In multivariate analysis, nonbilious vomiting, leukocytosis, and elevated CRP were significantly (P<0.05) associated with bowel gangrene. The resection rate for bowel gangrene was 44.9%, and no mortality was found. Seven (14.3%) patients had postoperative complications, including short-bowel syndrome (n=2), adhesion ileus (n=3), and intraabdominal abscess (n=3). Seven experienced failure to thrive in later follow-up. Conclusions: Specific clinical manifestations and laboratory parameters are helpful in the identification of bowel gangrene in children with SBV.

Original languageEnglish
Pages (from-to)417-422
Number of pages6
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume53
Issue number4
DOIs
StatePublished - 10 2011
Externally publishedYes

Keywords

  • bowel resection
  • children
  • intestinal gangrene
  • small-bowel volvulus

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