Role of cavum septum pellucidum in akinetic mutism of hydrocephalic children

Kuang Lin Lin, Huei Shyong Wang*, Ming Liang Chou, Tai Ngar Rui

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

6 Scopus citations


Two children 9 and 13 years of age with histories of aqueductal stenosis developed akinetic mutism after multiple shunt revisions. The girl had spontaneous relief of her akinetic mutism 1 month later, after parenteral antibiotics and multiple shunt revisions. The akinetic mutism of the boy was resistant to antiparkinsonian therapy before megadosage of bromocriptine (120 mg/day). Both children had a prominent cavum septum pellucidum (CSP), which has rarely been involved in the pathogenesis of akinetic mutism. Because of the rapid shrinkage of the girl's CSP after shunt revision, but not that of the boy even after stereotactic fenestration of the wall of his CSP, their eventual outcomes were different. Wide CSP (WCSP) may play an important role in the occurrence of akinetic mutism in hydrocephalic patients.

Original languageEnglish
Pages (from-to)156-159
Number of pages4
JournalPediatric Neurology
Issue number2
StatePublished - 02 1997
Externally publishedYes


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