Role of Urease Enzymes in Stability of a 10-Species Oral Biofilm Consortium Cultivated in a Constant-Depth Film Fermenter

Man Shu, Christopher M. Browngardt, Yi Ywan M. Chen, Robert A. Burne*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

48 Scopus citations

Abstract

Using a 10-species oral biofilm consortium and defined mutants, we show that high-level capacity to generate ammonia from a common salivary substrate is needed to maintain community diversity. This model appears to be suitable for the study of the effects of individual genetic determinants on the ecology of oral biofilms.

Original languageEnglish
Pages (from-to)7188-7192
Number of pages5
JournalInfection and Immunity
Volume71
Issue number12
DOIs
StatePublished - 12 2003
Externally publishedYes

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