Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies

Hsu Ming Chung; Wei Hsien Wang; Tsong Long Hwang; Lee Shing Fang; Zhi Hong Wen; Jih Jung Chen; Yang Chang Wu; Ping Jyun Sung

doi:10.3390/md12125856

Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies

Hsu Ming Chung, Wei Hsien Wang, Tsong Long Hwang, Lee Shing Fang, Zhi Hong Wen, Jih Jung Chen, Yang Chang Wu^*, Ping Jyun Sung

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

18 Scopus citations

Abstract

A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.

Original language	English
Pages (from-to)	5856-5863
Number of pages	8
Journal	Marine Drugs
Volume	12
Issue number	12
DOIs	https://doi.org/10.3390/md12125856
State	Published - 04 12 2014

Bibliographical note

Publisher Copyright:
© 2014 by the authors licensee MDPI Basel Switzerland.

Keywords

Elastase
Gorgonian
Rumphella antipathies
Rumphellaoic acid
Sesquiterpenoid

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10.3390/md12125856

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title = "Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies",

abstract = "A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.",

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AU - Chung, Hsu Ming

AU - Wang, Wei Hsien

AU - Hwang, Tsong Long

AU - Fang, Lee Shing

AU - Wen, Zhi Hong

AU - Chen, Jih Jung

AU - Wu, Yang Chang

AU - Sung, Ping Jyun

PY - 2014/12/4

Y1 - 2014/12/4

N2 - A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.

AB - A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.

KW - Elastase

KW - Gorgonian

KW - Rumphella antipathies

KW - Rumphellaoic acid

KW - Sesquiterpenoid

UR - http://www.scopus.com/inward/record.url?scp=84919787115&partnerID=8YFLogxK

U2 - 10.3390/md12125856

DO - 10.3390/md12125856

M3 - 文章

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AN - SCOPUS:84919787115

SN - 1660-3397

VL - 12

SP - 5856

EP - 5863

JO - Marine Drugs

JF - Marine Drugs

IS - 12

ER -

Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies

Abstract

Bibliographical note

Keywords

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