Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies

Hsu Ming Chung; Wei Hsien Wang; Tsong Long Hwang; Lee Shing Fang; Zhi Hong Wen; Jih Jung Chen; Yang Chang Wu; Ping Jyun Sung

doi:10.3390/md12125856

Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies

Hsu Ming Chung
, Wei Hsien Wang
, Tsong Long Hwang
, Lee Shing Fang
, Zhi Hong Wen
, Jih Jung Chen
, Yang Chang Wu^*
, Ping Jyun Sung

^*Corresponding author for this work

School of Traditional Chinese Medicine

National Pingtung University
National Sun Yat-sen University
National Museum of Marine Biology and Aquarium, Taiwan
Cheng Shiu University Taiwan
Tajen University
China Medical University Taichung
National Dong Hwa University
Kaohsiung Medical University

Research output: Contribution to journal › Journal Article › peer-review

18 Scopus citations

Abstract

A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.

Original language	English
Pages (from-to)	5856-5863
Number of pages	8
Journal	Marine Drugs
Volume	12
Issue number	12
DOIs	https://doi.org/10.3390/md12125856
State	Published - 04 12 2014

Bibliographical note

Publisher Copyright:
© 2014 by the authors licensee MDPI Basel Switzerland.

Keywords

Elastase
Gorgonian
Rumphella antipathies
Rumphellaoic acid
Sesquiterpenoid

Access to Document

10.3390/md12125856

Cite this

@article{bf1ae91a5fca4a5c8ddb17034e29de4f,

title = "Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies",

abstract = "A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.",

keywords = "Elastase, Gorgonian, Rumphella antipathies, Rumphellaoic acid, Sesquiterpenoid",

author = "Chung, \{Hsu Ming\} and Wang, \{Wei Hsien\} and Hwang, \{Tsong Long\} and Fang, \{Lee Shing\} and Wen, \{Zhi Hong\} and Chen, \{Jih Jung\} and Wu, \{Yang Chang\} and Sung, \{Ping Jyun\}",

note = "Publisher Copyright: {\textcopyright} 2014 by the authors licensee MDPI Basel Switzerland.",

year = "2014",

month = dec,

day = "4",

doi = "10.3390/md12125856",

language = "英语",

volume = "12",

pages = "5856--5863",

journal = "Marine Drugs",

issn = "1660-3397",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "12",

}

TY - JOUR

T1 - Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies

AU - Chung, Hsu Ming

AU - Wang, Wei Hsien

AU - Hwang, Tsong Long

AU - Fang, Lee Shing

AU - Wen, Zhi Hong

AU - Chen, Jih Jung

AU - Wu, Yang Chang

AU - Sung, Ping Jyun

PY - 2014/12/4

Y1 - 2014/12/4

N2 - A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.

AB - A novel sesquiterpenoid, rumphellaoic acid A ( 1), was isolated from the gorgonian coral Rumphella antipathies , and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils.

KW - Elastase

KW - Gorgonian

KW - Rumphella antipathies

KW - Rumphellaoic acid

KW - Sesquiterpenoid

UR - https://www.scopus.com/pages/publications/84919787115

U2 - 10.3390/md12125856

DO - 10.3390/md12125856

M3 - 文章

C2 - 25486110

AN - SCOPUS:84919787115

SN - 1660-3397

VL - 12

SP - 5856

EP - 5863

JO - Marine Drugs

JF - Marine Drugs

IS - 12

ER -

Rumphellaoic acid a, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this