Rumphellolide H, a new natural caryophyllane from the gorgonian rumphella antipathies

Tsong Long Hwang; Yin Di Su; Wan Ping Hu; Li Fan Chuang; Ping Jyun Sung

doi:10.3987/COM-08-11636

Rumphellolide H, a new natural caryophyllane from the gorgonian rumphella antipathies

Tsong Long Hwang^*, Yin Di Su, Wan Ping Hu, Li Fan Chuang, Ping Jyun Sung

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

17 Scopus citations

Abstract

A new natural caryophyllane-type sesquiterpenoid, rumphellolide H (1), which possesses a tetrahydropyran moiety in structure, was isolated from the gorgonian coral Rumphella antipathies. The structure of 1 was established by spectral data analysis and this metabolite showed moderate inhibitory effects on elastase release by human neutrophils.

Original language	English
Pages (from-to)	1563-1567
Number of pages	5
Journal	Heterocycles
Volume	78
Issue number	6
DOIs	https://doi.org/10.3987/COM-08-11636
State	Published - 01 06 2009

Keywords

Caryophyllane
Elastase
Gorgonian
Rumphella antipathies
Rumphellolide

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10.3987/COM-08-11636

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abstract = "A new natural caryophyllane-type sesquiterpenoid, rumphellolide H (1), which possesses a tetrahydropyran moiety in structure, was isolated from the gorgonian coral Rumphella antipathies. The structure of 1 was established by spectral data analysis and this metabolite showed moderate inhibitory effects on elastase release by human neutrophils.",

keywords = "Caryophyllane, Elastase, Gorgonian, Rumphella antipathies, Rumphellolide",

author = "Hwang, {Tsong Long} and Su, {Yin Di} and Hu, {Wan Ping} and Chuang, {Li Fan} and Sung, {Ping Jyun}",

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AU - Chuang, Li Fan

AU - Sung, Ping Jyun

PY - 2009/6/1

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AB - A new natural caryophyllane-type sesquiterpenoid, rumphellolide H (1), which possesses a tetrahydropyran moiety in structure, was isolated from the gorgonian coral Rumphella antipathies. The structure of 1 was established by spectral data analysis and this metabolite showed moderate inhibitory effects on elastase release by human neutrophils.

KW - Caryophyllane

KW - Elastase

KW - Gorgonian

KW - Rumphella antipathies

KW - Rumphellolide

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JO - Heterocycles

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Rumphellolide H, a new natural caryophyllane from the gorgonian rumphella antipathies

Abstract

Keywords

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