TY - JOUR
T1 - Scavenger receptors in innate immunity
AU - Peiser, Leanne
AU - Mukhopadhyay, Subhankar
AU - Gordon, Siamon
PY - 2002/2/1
Y1 - 2002/2/1
N2 - Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells. They bind and internalise micro-organisms and their products including Gram-positive bacteria (lipoteichoic acid), Gram-negative bacteria (lipopolysaccharide), intracellular bacteria and CpG DNA. SR can alter cell morphology and their expression is affected by various cytokines. SR are involved in lipid metabolism and bind modified low-density lipoproteins.
AB - Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells. They bind and internalise micro-organisms and their products including Gram-positive bacteria (lipoteichoic acid), Gram-negative bacteria (lipopolysaccharide), intracellular bacteria and CpG DNA. SR can alter cell morphology and their expression is affected by various cytokines. SR are involved in lipid metabolism and bind modified low-density lipoproteins.
UR - http://www.scopus.com/inward/record.url?scp=0036467584&partnerID=8YFLogxK
U2 - 10.1016/S0952-7915(01)00307-7
DO - 10.1016/S0952-7915(01)00307-7
M3 - 文献综述
C2 - 11790542
AN - SCOPUS:0036467584
SN - 0952-7915
VL - 14
SP - 123
EP - 128
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
IS - 1
ER -