Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid gland in a male patient: A case report and literature review

Chi Yun Lai, Tzu Chieh Chao, Jen Der Lin, Chuen Hsueh*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

22 Scopus citations

Abstract

Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) was first described by Chan et al in 1991. It is characterized by nest or strands of epidermoid tumor cells with squamous differentiation, rare mucous cells, prominent sclerotic stroma, eosinophilic and lymphoplasmacytic infiltration, and a background of chronic lymphocytic thyroiditis in the non-neoplastic thyroid gland. It is important to recognize SMECE of thyroid and differentiate it from squamous cell carcinoma or other neoplasms with squamous differentiation/metaplasia. In published cases, the SMECE of thyroid gland predominantly occurs in women. We report a case of SMECE of thyroid in a 45-year-old male patient. All cases in male patients were Caucasian described in English literature, and our case is the first one in Asian.

Original languageEnglish
Pages (from-to)5947-5951
Number of pages5
JournalInternational Journal of Clinical and Experimental Pathology
Volume8
Issue number5
StatePublished - 2015

Keywords

  • Eosinophilia
  • Hashimoto thyroiditis
  • Male
  • Sclerosing mucoepidermoid carcinoma
  • Thyroid gland

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