Section 8. Management of portal venous complications in pediatric living donor liver transplantation

  • Yu Fan Cheng
  • , Hsin You Ou
  • , Chun Yen Yu
  • , Leo Leung Chit Tsang
  • , Tung Liang Huang
  • , Tai Yi Chen
  • , Allan Concejero
  • , Chih Chi Wang
  • , Shih Ho Wang
  • , Tsan Shiun Lin
  • , Yueh Wei Liu
  • , Chin Hsiang Yang
  • , Chee Chien Yong
  • , King Wah Chiu
  • , Bruno Jawan
  • , Hock Liew Eng
  • , Chao Long Chen*
  • *Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

15 Scopus citations

Abstract

Portal vein (PV) complications after living donor liver transplant (LDLT) have been a major concern in pediatric liver transplantation. The incidence of PV complications is more in pediatric (0%-33%) than in adult recipients. Early diagnosis and treatment of PV complications may ensure optimal graft function and good recipient survival. Small preoperation PV size (<4 mm) and slow portal flow (<10 cm/s) combined with lower hepatic artery resistance index (<0.65) are strong warning signs that may predict the development of post LDLT PV complications. Portal vein angioplasty/stenting is conventionally performed through the percutaneous transhepatic approach; however, this can also be performed through transjugular, trans-splenic, and intraoperative approaches. Depending on the situation, using optimal method is the key point to minimize complication (5%) and gain high success rate (80%). PV occlusion of greater than 1 year with cavernous transformation seems to be a factor causing technical failure. Good patency rate (100%) with self-expandable metallic stents was noted in long-term follow-up. In conclusion, PV stent placement is an effective, long-term treatment modality to manage PV complications after pediatric LDLT. Early diagnosis and treatment are essential to maximize the use of stent placement and achieve good success rates.

Original languageEnglish
Pages (from-to)S32-S34
JournalTransplantation
Volume97
Issue number8
DOIs
StatePublished - 27 04 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Copyright 2014 by Lippincott Williams & Wilkins.

Keywords

  • Living donor liver transplantation
  • Pediatric liver transplantation
  • Portal vein complication
  • Portal vein occlusion
  • Stent

Fingerprint

Dive into the research topics of 'Section 8. Management of portal venous complications in pediatric living donor liver transplantation'. Together they form a unique fingerprint.

Cite this