Selective laser sintering of polycaprolactone coated with gelatin for cartilage tissue engineering

Chih Hao Chen*, Jyh Ping Chen, Ming Yih Lee

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The purpose of this study was to investigate the attachment and proliferation of cells on selective laser-sintered (SLS) polycaprolactone (PCL) scaffolds coated with gelatin for cartilage tissue engineering using chondrocytes isolated from the articular cartilage of swine. Scaffolds without modification were used as control groups. Cell proliferation was measured by cell count 1, 3 and 5 days after cell seeding into the scaffolds. The biocompatibility of the scaffold was examined by scanning electron microscopy (SEM). The PCL scaffolds coated with gelatin had higher hydrophilicity. The results provided a useful strategy for modifying the microenvironments to increase cell attachment, growth and the formation of extracellular matrix on scaffolds for cartilage tissue engineering.

Original languageEnglish
Title of host publicationISOB 2011 - Proceedings of the 1st International Symposium on Bioengineering
Pages290-298
Number of pages9
DOIs
StatePublished - 2011
Event1st International Symposium on Bioengineering, ISOB 2011 - Singapore, Singapore
Duration: 19 01 201119 01 2011

Publication series

NameISOB 2011 - Proceedings of the 1st International Symposium ISOB 2011 - Proceedings of the 1st International Symposium on Bioengineering

Conference

Conference1st International Symposium on Bioengineering, ISOB 2011
Country/TerritorySingapore
CitySingapore
Period19/01/1119/01/11

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