Sequential organ failure assessment score predicts mortality after coronary artery bypass grafting

Chih Hsiang Chang, Shao Wei Chen, Pei Chun Fan, Cheng Chia Lee, Huang Yu Yang, Su Wei Chang, Heng Chih Pan, Feng Chun Tsai, Chih Wei Yang, Yung Chang Chen*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

15 Scopus citations


Background: Mortality after coronary artery bypass grafting (CABG) is generally associated with underlying disease and surgical factors overlooked in preoperative prognostic models. Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores are widely used in intensive care units for outcome prediction. This study investigated the accuracy of these models in predicting mortality. Methods: Between January 2010 and April 2013, 483 patients who underwent isolated CABG were enrolled. The clinical characteristics, outcomes, and prognostic model scores of the patients were collected. Discrimination was assessed using the area under the curve approach. Results: Both SOFA and APACHE II scores were effective for predicting in-hospital mortality. Among the organ systems examined in the SOFA, the cardiac and renal systems were the strongest predictors of CABG mortality. Multivariate analysis identified only the SOFA score as being an independent risk factor for mortality. Conclusion: In summary, the SOFA score can be used to accurately identify mortality after isolated CABG.

Original languageEnglish
Article number22
JournalBMC Surgery
Issue number1
StatePublished - 06 03 2017

Bibliographical note

Publisher Copyright:
© 2017 The Author(s).


  • Cardiorenal syndrome
  • Coronary artery by pass grafting
  • Mortality
  • Sequential organ failure assessment
  • Society of thoracic surgeons mortality risk


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