Sesquiterpene esters of aristolochic acid from the root and stem of Aristolochia heterophylla

Tian Shung Wu; Yu Yi Chan; Yann Lii Leu; Zong Tsi Chen

doi:10.1021/np980212y

Sesquiterpene esters of aristolochic acid from the root and stem of Aristolochia heterophylla

Tian Shung Wu^*
, Yu Yi Chan
, Yann Lii Leu
, Zong Tsi Chen

^*Corresponding author for this work

National Cheng Kung University
Chia Nan University of Pharmacy and Science

Research output: Contribution to journal › Journal Article › peer-review

22 Scopus citations

Abstract

Three novel sesquiterpene esters of aristolochic acid, aristoloterpenate-II (2), -III (3), and-IV (4), together with known aristoloterpenate-I (1), were isolated and characterized from the root and stem of Aristolochia heterophylla. Their structures were elucidated by spectroscopic methods. The absolute configuration of these compounds at C-4' was determined as R by circular dichroic studies. These compounds showed cytotoxicity against hepatoma G2, 2, 2, 15 cells.

Original language	English
Pages (from-to)	415-418
Number of pages	4
Journal	Journal of Natural Products
Volume	62
Issue number	3
DOIs	https://doi.org/10.1021/np980212y
State	Published - 03 1999
Externally published	Yes

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title = "Sesquiterpene esters of aristolochic acid from the root and stem of Aristolochia heterophylla",

abstract = "Three novel sesquiterpene esters of aristolochic acid, aristoloterpenate-II (2), -III (3), and-IV (4), together with known aristoloterpenate-I (1), were isolated and characterized from the root and stem of Aristolochia heterophylla. Their structures were elucidated by spectroscopic methods. The absolute configuration of these compounds at C-4' was determined as R by circular dichroic studies. These compounds showed cytotoxicity against hepatoma G2, 2, 2, 15 cells.",

author = "Wu, \{Tian Shung\} and Chan, \{Yu Yi\} and Leu, \{Yann Lii\} and Chen, \{Zong Tsi\}",

year = "1999",

month = mar,

doi = "10.1021/np980212y",

language = "英语",

volume = "62",

pages = "415--418",

journal = "Journal of Natural Products",

issn = "0163-3864",

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T1 - Sesquiterpene esters of aristolochic acid from the root and stem of Aristolochia heterophylla

AU - Wu, Tian Shung

AU - Chan, Yu Yi

AU - Leu, Yann Lii

AU - Chen, Zong Tsi

PY - 1999/3

Y1 - 1999/3

N2 - Three novel sesquiterpene esters of aristolochic acid, aristoloterpenate-II (2), -III (3), and-IV (4), together with known aristoloterpenate-I (1), were isolated and characterized from the root and stem of Aristolochia heterophylla. Their structures were elucidated by spectroscopic methods. The absolute configuration of these compounds at C-4' was determined as R by circular dichroic studies. These compounds showed cytotoxicity against hepatoma G2, 2, 2, 15 cells.

AB - Three novel sesquiterpene esters of aristolochic acid, aristoloterpenate-II (2), -III (3), and-IV (4), together with known aristoloterpenate-I (1), were isolated and characterized from the root and stem of Aristolochia heterophylla. Their structures were elucidated by spectroscopic methods. The absolute configuration of these compounds at C-4' was determined as R by circular dichroic studies. These compounds showed cytotoxicity against hepatoma G2, 2, 2, 15 cells.

UR - https://www.scopus.com/pages/publications/0032946381

U2 - 10.1021/np980212y

DO - 10.1021/np980212y

M3 - 文章

C2 - 10096848

AN - SCOPUS:0032946381

SN - 0163-3864

VL - 62

SP - 415

EP - 418

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 3

ER -

Sesquiterpene esters of aristolochic acid from the root and stem of Aristolochia heterophylla

Abstract

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