Short report: Impact of HAART therapy on co-infection of tuberculosis and HIV cases for 9 years in Taiwan

Shu Hui Tseng, Donald Dah Shyong Jiang, Hao Seong Hoi, Shiang Lin Yang, Kao Pin Hwang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

5 Scopus citations

Abstract

Free highly active antiretroviral therapy (HAART) was made available by The Department of Health since April 1997. As a result, the incidence rate of tuberculosis (TB)/human immunodeficiency virus (HIV) co-infection among HIV cases rose from 1.90% to 3.82% during 1993 to 1998 and decreased from 3.82% to 0.94% during 1998 to 2006. The incidence rate of TB/HIV co-infection among HIV cases reached its peak in 1998 and then started to reverse, although the next year the TB disease burden (incidence rate: 62.7 cases per 100,000 persons) remained consistently high, and this continued in the following years. The survival rate of TB/HIV co-infection cases was 62.16% during the period 1993-1996 (pre-free HAART era) and increased to 86.60% during the period 1998-2006 (P < 0.0001) (post-free HAART era). Highly active antiretroviral therapy decreased the incidence rate of new TB/HIV co-infection cases among HIV cases and increased the survival rate of TB/HIV co-infection cases.

Original languageEnglish
Pages (from-to)675-677
Number of pages3
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume80
Issue number4
DOIs
StatePublished - 04 2009
Externally publishedYes

Keywords

  • ACTIVE ANTIRETROVIRAL THERAPY
  • ADULTS
  • COHORT
  • DISEASE PROGRESSION
  • EPIDEMIOLOGY
  • ERA
  • HUMAN-IMMUNODEFICIENCY-VIRUS
  • INFECTION
  • RISK
  • SURVIVAL

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