Similar survival after endoscopic submucosal dissection and esophagectomy in early esophageal cancer and synchronous or metachronous head and neck cancer

Ruei Ti Ke, Yu Hsin Hsiao, Wei Chen Tai, Shau Hsuan Li, Chih Chien Yao, Kai Hao Chuang, Hsing Hua Lai, Yu Chen, Li Chun Chen, Hung I. Lu, Yen Hao Chen, Chien Ming Lo*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

Abstract

Background: Early-stage esophageal cancer is treated using endoscopic submucosal dissection and esophagectomy. Field cancerization in patients with early-stage esophageal cancer affects treatment outcomes and causes synchronous or metachronous head and neck cancers. We hypothesized that esophagectomy could provide better overall and relapse-free survivals in patients with esophageal cancer and synchronous or metachronous head and neck cancer. Methods: We retrospectively identified patients with early esophageal squamous cell carcinoma and synchronous or metachronous head and neck cancers. We separated the patients into endoscopic submucosal dissection and esophagectomy groups to compare overall and relapse-free survivals. Results: The study included 106 patients, 25 of whom underwent endoscopic submucosal dissection and 81 underwent esophagectomy. Overall and relapse-free survivals did not show significant differences between the two groups for both synchronous and metachronous head and neck cancers. Conclusions: Endoscopic submucosal dissection could provide similar overall and relapse-free survivals in patients with esophageal cancer and synchronous or metachronous head and neck cancer.

Original languageEnglish
Pages (from-to)52
JournalJournal of Cardiothoracic Surgery
Volume19
Issue number1
DOIs
StatePublished - 04 02 2024

Bibliographical note

© 2024. The Author(s).

Keywords

  • Early-stage esophageal cancer
  • Endoscopic submucosal dissection
  • Esophagectomy
  • Synchronous and metachronous head and neck cancer
  • Carcinoma, Squamous Cell
  • Esophageal Neoplasms/pathology
  • Endoscopic Mucosal Resection
  • Humans
  • Retrospective Studies
  • Esophageal Squamous Cell Carcinoma/surgery
  • Neoplasm Recurrence, Local/surgery
  • Head and Neck Neoplasms

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