Abstract
This chapter reviews recent technical developments in the field of single-cell electrical property characterization. Firstly, three well-established characterization approaches including patch clamping, electrorotation, and dielectrophoresis are discussed and compared. Then, key developments of impedance flow cytometry, which are capable of high-throughput quantifying single-cell electrical properties, are presented. In addition, key cellular electrical properties quantified by these techniques are summarized and discussed. In the end, future research opportunities with technical innovations are indicated.
Original language | English |
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Title of host publication | Handbook of Single-Cell Technologies |
Publisher | Springer Singapore |
Pages | 889-919 |
Number of pages | 31 |
ISBN (Electronic) | 9789811089534 |
ISBN (Print) | 9789811089527 |
DOIs | |
State | Published - 01 01 2021 |
Bibliographical note
Publisher Copyright:© Springer Nature Singapore Pte Ltd, part of Springer Nature 2022.
Keywords
- Cellular bioelectrical characterization
- Dielectrophoresis
- Electrorotation
- Impedance flow cytometry
- Patch clamping
- Single-cell analysis