Spinal epidural Rosai-Dorfman disease preceding by relapsing uveitis: A case report with literature review

Y. C. Huang, H. Y. Tan, S. M. Jung, W. Y. Chuang, C. C. Chuang, P. W. Hsu, Chen-Nen Chang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

15 Scopus citations

Abstract

Study design: Case report. Setting: Tertiary referral center hospital in Taiwan. Objectives: To report a case of spinal Rosai-Dorfman disease (RDD) presenting with paraparesis and also preceding by relapsing uveitis for 6 months. A thoracic laminectomy was performed to remove the solid mass. The pathological diagnosis reveals infiltrating histiocytes, emperipolesis and positivity for S-100. There is no recurrence 1 year later with MR imaging. Conclusions: The relapsing idiopathic uveitis may be a prodrome for this unusual disease, because RDD is associated closely to defective immunogical response. Early and accurate diagnosis of CNS RDD may reverse the neurologic deficits by early decompression.

Original languageEnglish
Pages (from-to)641-644
Number of pages4
JournalSpinal Cord
Volume45
Issue number9
DOIs
StatePublished - 07 09 2007

Keywords

  • Rosai-Dorfman disease
  • Sinus histiocytosis
  • Spinal neoplasm
  • Uveitis

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