Abstract
What is known and objective: Although the risk of major bleeding with non-vitamin K antagonist oral anticoagulant (NOAC) is low, life-threatening bleeding can occur. Case summary: We report a case of an 81-year-old female with deep vein thrombosis who developed bilateral spontaneous haemothorax and haemopericardium after rivaroxaban therapy. Diagnostic thoracentesis revealed a grossly bloody pleural effusion. She was treated with factor eight inhibitor bypassing agent, but the result was not satisfactory. What is new and conclusion: To our knowledge, this is the first case report of a concomitant presentation of spontaneous bilateral haemothorax and haemopericardium due to rivaroxaban use. This case highlights the potential risk of major haemorrhagic complication of NOAC, which could be life-threatening and require emergent reversal.
| Original language | English |
|---|---|
| Pages (from-to) | 1175-1178 |
| Number of pages | 4 |
| Journal | Journal of Clinical Pharmacy and Therapeutics |
| Volume | 45 |
| Issue number | 5 |
| DOIs | |
| State | Published - 01 10 2020 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2020 John Wiley & Sons Ltd
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This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- factor Xa inhibitors
- haemopericardium
- non-vitamin K antagonist oral anticoagulants
- rivaroxaban
- spontaneous haemothorax
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