Stem Cell Therapy in Children with Traumatic Brain Injury

Wen Ya Lin; Kang Hsi Wu; Chun Yu Chen; Bei Cyuan Guo; Yu Jun Chang; Tai An Lee; Mao Jen Lin; Han Ping Wu

doi:10.3390/ijms241914706

Stem Cell Therapy in Children with Traumatic Brain Injury

Wen Ya Lin, Kang Hsi Wu, Chun Yu Chen, Bei Cyuan Guo, Yu Jun Chang, Tai An Lee, Mao Jen Lin^*, Han Ping Wu^*

^*Corresponding author for this work

School of Medicine

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Pediatric traumatic brain injury is a cause of major mortality, and resultant neurological sequelae areassociated with long-term morbidity. Increasing studies have revealed stem cell therapy to be a potential new treatment. However, much work is still required to clarify the mechanism of action of effective stem cell therapy, type of stem cell therapy, optimal timing of therapy initiation, combination of cocurrent medical treatment and patient selection criteria. This paper will focus on stem cell therapy in children with traumatic brain injury.

Original language	English
Article number	14706
Journal	International Journal of Molecular Sciences
Volume	24
Issue number	19
DOIs	https://doi.org/10.3390/ijms241914706
State	Published - 10 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Keywords

bone marrow mononuclear cells
children
mesenchymal stem cells
stem cell therapy
traumatic brain injury

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10.3390/ijms241914706

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title = "Stem Cell Therapy in Children with Traumatic Brain Injury",

abstract = "Pediatric traumatic brain injury is a cause of major mortality, and resultant neurological sequelae areassociated with long-term morbidity. Increasing studies have revealed stem cell therapy to be a potential new treatment. However, much work is still required to clarify the mechanism of action of effective stem cell therapy, type of stem cell therapy, optimal timing of therapy initiation, combination of cocurrent medical treatment and patient selection criteria. This paper will focus on stem cell therapy in children with traumatic brain injury.",

keywords = "bone marrow mononuclear cells, children, mesenchymal stem cells, stem cell therapy, traumatic brain injury",

author = "Lin, {Wen Ya} and Wu, {Kang Hsi} and Chen, {Chun Yu} and Guo, {Bei Cyuan} and Chang, {Yu Jun} and Lee, {Tai An} and Lin, {Mao Jen} and Wu, {Han Ping}",

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AU - Lin, Wen Ya

AU - Wu, Kang Hsi

AU - Chen, Chun Yu

AU - Guo, Bei Cyuan

AU - Chang, Yu Jun

AU - Lee, Tai An

AU - Lin, Mao Jen

AU - Wu, Han Ping

PY - 2023/10

Y1 - 2023/10

N2 - Pediatric traumatic brain injury is a cause of major mortality, and resultant neurological sequelae areassociated with long-term morbidity. Increasing studies have revealed stem cell therapy to be a potential new treatment. However, much work is still required to clarify the mechanism of action of effective stem cell therapy, type of stem cell therapy, optimal timing of therapy initiation, combination of cocurrent medical treatment and patient selection criteria. This paper will focus on stem cell therapy in children with traumatic brain injury.

AB - Pediatric traumatic brain injury is a cause of major mortality, and resultant neurological sequelae areassociated with long-term morbidity. Increasing studies have revealed stem cell therapy to be a potential new treatment. However, much work is still required to clarify the mechanism of action of effective stem cell therapy, type of stem cell therapy, optimal timing of therapy initiation, combination of cocurrent medical treatment and patient selection criteria. This paper will focus on stem cell therapy in children with traumatic brain injury.

KW - bone marrow mononuclear cells

KW - children

KW - mesenchymal stem cells

KW - stem cell therapy

KW - traumatic brain injury

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U2 - 10.3390/ijms241914706

DO - 10.3390/ijms241914706

M3 - 文献综述

C2 - 37834152

AN - SCOPUS:85174742781

SN - 1661-6596

VL - 24

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

IS - 19

M1 - 14706

ER -

Stem Cell Therapy in Children with Traumatic Brain Injury

Abstract

Bibliographical note

Keywords

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