Abstract
Two new sterols, columnaristerols B (1) and C (2), along with two known analogues, 5,6-epoxylitosterol (3) and litosterol (4), were obtained from the octocoral Nephthea columnaris. The structures of new sterols 1 and 2 were elucidated by using spectroscopic methods and comparing the spectroscopic data with those of known related metabolites. Sterol 3 was found to suppress superoxide anion production and elastase secretion by human neutrophils.
Original language | English |
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Article number | 212 |
Journal | Marine Drugs |
Volume | 15 |
Issue number | 7 |
DOIs | |
State | Published - 07 2017 |
Bibliographical note
Publisher Copyright:© 2017 by the authors. Licensee MDPI.
Keywords
- Columnaristerol
- Elastase
- Litosterol
- Nephthea columnaris
- Octocoral
- Superoxide anion