Studies on the Formosan Soft Corals I‐Cytotoxic Cembrane Diterpenes from Sarcophyton Trocheliophorum

Yang‐Chang ‐C Wu; Pei‐Wen ‐W Hsieh; Chang‐Yih ‐Y Duh; Shang‐Kwei ‐K Wang; Keryea Soong; Lee‐Shing ‐S Fang

doi:10.1002/jccs.199200062

Studies on the Formosan Soft Corals I‐Cytotoxic Cembrane Diterpenes from Sarcophyton Trocheliophorum

Yang‐Chang ‐C Wu^*
, Pei‐Wen ‐W Hsieh
, Chang‐Yih ‐Y Duh
, Shang‐Kwei ‐K Wang
, Keryea Soong
, Lee‐Shing ‐S Fang

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

11 Scopus citations

Abstract

Two cytotoxic cembranoid diterpenes, (+)‐isosarcophytoxide (1) and ( + )‐isosarcophine (2), were isolated from the soft coral Sarcophyton trocheliophorum by cytotoxicity‐guided fractionation. These two compounds demonstrated potent cytotoxicity against P‐388 and HL‐60 cells.

Original language	English
Pages (from-to)	355-357
Number of pages	3
Journal	Journal of the Chinese Chemical Society
Volume	39
Issue number	4
DOIs	https://doi.org/10.1002/jccs.199200062
State	Published - 08 1992
Externally published	Yes

Keywords

Cembrane diterpenes
Cytotoxicity
Sarcophyton trocheliophorum
Soft coral

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10.1002/jccs.199200062

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title = "Studies on the Formosan Soft Corals I‐Cytotoxic Cembrane Diterpenes from Sarcophyton Trocheliophorum",

abstract = "Two cytotoxic cembranoid diterpenes, (+)‐isosarcophytoxide (1) and ( + )‐isosarcophine (2), were isolated from the soft coral Sarcophyton trocheliophorum by cytotoxicity‐guided fractionation. These two compounds demonstrated potent cytotoxicity against P‐388 and HL‐60 cells.",

keywords = "Cembrane diterpenes, Cytotoxicity, Sarcophyton trocheliophorum, Soft coral",

author = "Wu, \{Yang‐Chang ‐C\} and Hsieh, \{Pei‐Wen ‐W\} and Duh, \{Chang‐Yih ‐Y\} and Wang, \{Shang‐Kwei ‐K\} and Keryea Soong and Fang, \{Lee‐Shing ‐S\}",

year = "1992",

month = aug,

doi = "10.1002/jccs.199200062",

language = "英语",

volume = "39",

pages = "355--357",

journal = "Journal of the Chinese Chemical Society",

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TY - JOUR

T1 - Studies on the Formosan Soft Corals I‐Cytotoxic Cembrane Diterpenes from Sarcophyton Trocheliophorum

AU - Wu, Yang‐Chang ‐C

AU - Hsieh, Pei‐Wen ‐W

AU - Duh, Chang‐Yih ‐Y

AU - Wang, Shang‐Kwei ‐K

AU - Soong, Keryea

AU - Fang, Lee‐Shing ‐S

PY - 1992/8

Y1 - 1992/8

N2 - Two cytotoxic cembranoid diterpenes, (+)‐isosarcophytoxide (1) and ( + )‐isosarcophine (2), were isolated from the soft coral Sarcophyton trocheliophorum by cytotoxicity‐guided fractionation. These two compounds demonstrated potent cytotoxicity against P‐388 and HL‐60 cells.

AB - Two cytotoxic cembranoid diterpenes, (+)‐isosarcophytoxide (1) and ( + )‐isosarcophine (2), were isolated from the soft coral Sarcophyton trocheliophorum by cytotoxicity‐guided fractionation. These two compounds demonstrated potent cytotoxicity against P‐388 and HL‐60 cells.

KW - Cembrane diterpenes

KW - Cytotoxicity

KW - Sarcophyton trocheliophorum

KW - Soft coral

UR - https://www.scopus.com/pages/publications/84986513618

U2 - 10.1002/jccs.199200062

DO - 10.1002/jccs.199200062

M3 - 文章

AN - SCOPUS:84986513618

SN - 0009-4536

VL - 39

SP - 355

EP - 357

JO - Journal of the Chinese Chemical Society

JF - Journal of the Chinese Chemical Society

IS - 4

ER -

Studies on the Formosan Soft Corals I‐Cytotoxic Cembrane Diterpenes from Sarcophyton Trocheliophorum

Abstract

Keywords

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