Study of photon migration with various sourcedetector separations in near-infrared spectroscopic brain imaging based on threedimensional monte carlo modeling

Cheng Kuang Lee; Chia Wei Sun; Po Lei Lee; Hsiang Chieh Lee; C. C. Yang; Cho Pei Jiang; Yuh Ping Tong; Tzu Chen Yeh; Jen Chuen Hsieh

doi:10.1364/OPEX.13.008339

Study of photon migration with various sourcedetector separations in near-infrared spectroscopic brain imaging based on threedimensional monte carlo modeling

Cheng Kuang Lee, Chia Wei Sun, Po Lei Lee, Hsiang Chieh Lee, C. C. Yang, Cho Pei Jiang, Yuh Ping Tong, Tzu Chen Yeh, Jen Chuen Hsieh

Research output: Contribution to journal › Journal Article › peer-review

29 Scopus citations

Abstract

We have simulated the photon migration with various sourcedetector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed.

Original language	English
Pages (from-to)	8339-8348
Number of pages	10
Journal	Optics Express
Volume	13
Issue number	21
DOIs	https://doi.org/10.1364/OPEX.13.008339
State	Published - 17 10 2005
Externally published	Yes

Access to Document

10.1364/OPEX.13.008339

Cite this

@article{cd05014627f1411c9ef2832e46e79427,

title = "Study of photon migration with various sourcedetector separations in near-infrared spectroscopic brain imaging based on threedimensional monte carlo modeling",

abstract = "We have simulated the photon migration with various sourcedetector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed.",

author = "Lee, {Cheng Kuang} and Sun, {Chia Wei} and Lee, {Po Lei} and Lee, {Hsiang Chieh} and Yang, {C. C.} and Jiang, {Cho Pei} and Tong, {Yuh Ping} and Yeh, {Tzu Chen} and Hsieh, {Jen Chuen}",

year = "2005",

month = oct,

day = "17",

doi = "10.1364/OPEX.13.008339",

language = "英语",

volume = "13",

pages = "8339--8348",

journal = "Optics Express",

issn = "1094-4087",

number = "21",

}

TY - JOUR

T1 - Study of photon migration with various sourcedetector separations in near-infrared spectroscopic brain imaging based on threedimensional monte carlo modeling

AU - Lee, Cheng Kuang

AU - Sun, Chia Wei

AU - Lee, Po Lei

AU - Lee, Hsiang Chieh

AU - Yang, C. C.

AU - Jiang, Cho Pei

AU - Tong, Yuh Ping

AU - Yeh, Tzu Chen

AU - Hsieh, Jen Chuen

PY - 2005/10/17

Y1 - 2005/10/17

N2 - We have simulated the photon migration with various sourcedetector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed.

AB - We have simulated the photon migration with various sourcedetector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed.

UR - http://www.scopus.com/inward/record.url?scp=26844506799&partnerID=8YFLogxK

U2 - 10.1364/OPEX.13.008339

DO - 10.1364/OPEX.13.008339

M3 - 文章

AN - SCOPUS:26844506799

SN - 1094-4087

VL - 13

SP - 8339

EP - 8348

JO - Optics Express

JF - Optics Express

IS - 21

ER -

Study of photon migration with various sourcedetector separations in near-infrared spectroscopic brain imaging based on threedimensional monte carlo modeling

Abstract

Access to Document

Other files and links

Fingerprint

Cite this