Study on composite calcium phosphate bone cement added with gamma-PGA

Ren-Jei Chung; Keng-Liang Ou; Ping-Wen Tsai; Hsuan-Liang Liu; Ching-Wen Huang; Wei-Jen Shih; Jui-Sheng Lee; Jen-Ming Yang

Study on composite calcium phosphate bone cement added with gamma-PGA

Ren-Jei Chung, Keng-Liang Ou, Ping-Wen Tsai, Hsuan-Liang Liu, Ching-Wen Huang, Wei-Jen Shih, Jui-Sheng Lee, Jen-Ming Yang

Department of Chemical and Materials Engineering

Research output: Contribution to journal › Journal Article › peer-review

Abstract

Development of hard tissue restoration material for human is one of important issues around the world. Calcium phosphate cement (CPC) has good biocompatibility and plasticity, and has been used in orthopedic, dental field and other relative fields gradually. In this experiment, we prepared a composite CPC made of tetracalcium phosphate (TTCP). The complex bone cement composed of CPC and gamma-poly glutamic acid (gamma-PGA) was prepared and tested. The composite bone cement has the features including biodegradability and better biocompatibility. The result of mechanical measurement showed that 12.5% gamma-PGA cement had a compressive strength of 24.8MPa. This composite bone cement is expected to have improved properties and able to be used as restoration material.

Original language	American English
Pages (from-to)	29-33
Journal	JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY
Volume	52
Issue number	1
State	Published - 2016

Keywords

Biocompatibility
Bone Cement
TETRACALCIUM PHOSPHATE
Tetracalcium Phosphate
gamma-poly Glutamic Acid

Cite this

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title = "Study on composite calcium phosphate bone cement added with gamma-PGA",

abstract = "Development of hard tissue restoration material for human is one of important issues around the world. Calcium phosphate cement (CPC) has good biocompatibility and plasticity, and has been used in orthopedic, dental field and other relative fields gradually. In this experiment, we prepared a composite CPC made of tetracalcium phosphate (TTCP). The complex bone cement composed of CPC and gamma-poly glutamic acid (gamma-PGA) was prepared and tested. The composite bone cement has the features including biodegradability and better biocompatibility. The result of mechanical measurement showed that 12.5% gamma-PGA cement had a compressive strength of 24.8MPa. This composite bone cement is expected to have improved properties and able to be used as restoration material.",

keywords = "Biocompatibility, Bone Cement, TETRACALCIUM PHOSPHATE, Tetracalcium Phosphate, gamma-poly Glutamic Acid",

author = "Ren-Jei Chung and Keng-Liang Ou and Ping-Wen Tsai and Hsuan-Liang Liu and Ching-Wen Huang and Wei-Jen Shih and Jui-Sheng Lee and Jen-Ming Yang",

year = "2016",

language = "American English",

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TY - JOUR

T1 - Study on composite calcium phosphate bone cement added with gamma-PGA

AU - Chung, Ren-Jei

AU - Ou, Keng-Liang

AU - Tsai, Ping-Wen

AU - Liu, Hsuan-Liang

AU - Huang, Ching-Wen

AU - Shih, Wei-Jen

AU - Lee, Jui-Sheng

AU - Yang, Jen-Ming

PY - 2016

Y1 - 2016

N2 - Development of hard tissue restoration material for human is one of important issues around the world. Calcium phosphate cement (CPC) has good biocompatibility and plasticity, and has been used in orthopedic, dental field and other relative fields gradually. In this experiment, we prepared a composite CPC made of tetracalcium phosphate (TTCP). The complex bone cement composed of CPC and gamma-poly glutamic acid (gamma-PGA) was prepared and tested. The composite bone cement has the features including biodegradability and better biocompatibility. The result of mechanical measurement showed that 12.5% gamma-PGA cement had a compressive strength of 24.8MPa. This composite bone cement is expected to have improved properties and able to be used as restoration material.

AB - Development of hard tissue restoration material for human is one of important issues around the world. Calcium phosphate cement (CPC) has good biocompatibility and plasticity, and has been used in orthopedic, dental field and other relative fields gradually. In this experiment, we prepared a composite CPC made of tetracalcium phosphate (TTCP). The complex bone cement composed of CPC and gamma-poly glutamic acid (gamma-PGA) was prepared and tested. The composite bone cement has the features including biodegradability and better biocompatibility. The result of mechanical measurement showed that 12.5% gamma-PGA cement had a compressive strength of 24.8MPa. This composite bone cement is expected to have improved properties and able to be used as restoration material.

KW - Biocompatibility

KW - Bone Cement

KW - TETRACALCIUM PHOSPHATE

KW - Tetracalcium Phosphate

KW - gamma-poly Glutamic Acid

M3 - Journal Article

SN - 2510-1560

VL - 52

SP - 29

EP - 33

JO - JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY

JF - JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY

IS - 1

ER -

Study on composite calcium phosphate bone cement added with gamma-PGA

Abstract

Keywords

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