Stunning effects after a diagnostic dose of Iodine-131

Chia Hung Kao; Tzu Chen Yen

doi:10.1055/s-0038-1629854

Stunning effects after a diagnostic dose of Iodine-131

Chia Hung Kao^*, Tzu Chen Yen

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

43 Scopus citations

Abstract

Aim: To understand stunning effects of a diagnostic dose of iodine-131 (I-131). Methods: Four hundred and sixty-eight patients (101 males, 367 females, ages: 6-75 years) with well differentiated thyroid cancer, following total or nearly total thyroidectomy, were studied. One hundred and eleven MBq (3 mCi) diagnostic (Dx) doses of I-131 whole body scan (WBS) were obtained after withholding thyroxine after 6 weeks and triiodothyronine for 2 weeks. One week to one month later, 3.7-7.4 GBq (100-200 mCi) I-131 was given to them, then simulating hormone level was usually above 30 μIU/ml. Results: Of the 468 patients, 344 (73.5%) has scintigraphic patterns of apparently decreased uptake in 240 thyroid remnants and 104 metastatic lesions on the Tx dose of I-131 WBS compared to Dx dose of I-131 WBS. Stunning phenomenon occurred in 50 cases, including 42 thyroid remnants and 18 metastatic lesions. Conclusion: Dx dose of I-131 influence the uptake of a subsequently administered Tx dose of I-131.

Original language	English
Pages (from-to)	23-25
Number of pages	3
Journal	NuklearMedizin
Volume	37
Issue number	1
DOIs	https://doi.org/10.1055/s-0038-1629854
State	Published - 01 1998
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1055/s-0038-1629854

Cite this

@article{c2195ae9232548129066bbfbd258e7d0,

title = "Stunning effects after a diagnostic dose of Iodine-131",

abstract = "Aim: To understand stunning effects of a diagnostic dose of iodine-131 (I-131). Methods: Four hundred and sixty-eight patients (101 males, 367 females, ages: 6-75 years) with well differentiated thyroid cancer, following total or nearly total thyroidectomy, were studied. One hundred and eleven MBq (3 mCi) diagnostic (Dx) doses of I-131 whole body scan (WBS) were obtained after withholding thyroxine after 6 weeks and triiodothyronine for 2 weeks. One week to one month later, 3.7-7.4 GBq (100-200 mCi) I-131 was given to them, then simulating hormone level was usually above 30 μIU/ml. Results: Of the 468 patients, 344 (73.5%) has scintigraphic patterns of apparently decreased uptake in 240 thyroid remnants and 104 metastatic lesions on the Tx dose of I-131 WBS compared to Dx dose of I-131 WBS. Stunning phenomenon occurred in 50 cases, including 42 thyroid remnants and 18 metastatic lesions. Conclusion: Dx dose of I-131 influence the uptake of a subsequently administered Tx dose of I-131.",

author = "Kao, {Chia Hung} and Yen, {Tzu Chen}",

year = "1998",

month = jan,

doi = "10.1055/s-0038-1629854",

language = "英语",

volume = "37",

pages = "23--25",

journal = "NuklearMedizin",

issn = "0029-5566",

publisher = "Georg Thieme Verlag",

number = "1",

}

TY - JOUR

T1 - Stunning effects after a diagnostic dose of Iodine-131

AU - Kao, Chia Hung

AU - Yen, Tzu Chen

PY - 1998/1

Y1 - 1998/1

N2 - Aim: To understand stunning effects of a diagnostic dose of iodine-131 (I-131). Methods: Four hundred and sixty-eight patients (101 males, 367 females, ages: 6-75 years) with well differentiated thyroid cancer, following total or nearly total thyroidectomy, were studied. One hundred and eleven MBq (3 mCi) diagnostic (Dx) doses of I-131 whole body scan (WBS) were obtained after withholding thyroxine after 6 weeks and triiodothyronine for 2 weeks. One week to one month later, 3.7-7.4 GBq (100-200 mCi) I-131 was given to them, then simulating hormone level was usually above 30 μIU/ml. Results: Of the 468 patients, 344 (73.5%) has scintigraphic patterns of apparently decreased uptake in 240 thyroid remnants and 104 metastatic lesions on the Tx dose of I-131 WBS compared to Dx dose of I-131 WBS. Stunning phenomenon occurred in 50 cases, including 42 thyroid remnants and 18 metastatic lesions. Conclusion: Dx dose of I-131 influence the uptake of a subsequently administered Tx dose of I-131.

AB - Aim: To understand stunning effects of a diagnostic dose of iodine-131 (I-131). Methods: Four hundred and sixty-eight patients (101 males, 367 females, ages: 6-75 years) with well differentiated thyroid cancer, following total or nearly total thyroidectomy, were studied. One hundred and eleven MBq (3 mCi) diagnostic (Dx) doses of I-131 whole body scan (WBS) were obtained after withholding thyroxine after 6 weeks and triiodothyronine for 2 weeks. One week to one month later, 3.7-7.4 GBq (100-200 mCi) I-131 was given to them, then simulating hormone level was usually above 30 μIU/ml. Results: Of the 468 patients, 344 (73.5%) has scintigraphic patterns of apparently decreased uptake in 240 thyroid remnants and 104 metastatic lesions on the Tx dose of I-131 WBS compared to Dx dose of I-131 WBS. Stunning phenomenon occurred in 50 cases, including 42 thyroid remnants and 18 metastatic lesions. Conclusion: Dx dose of I-131 influence the uptake of a subsequently administered Tx dose of I-131.

UR - http://www.scopus.com/inward/record.url?scp=0031846080&partnerID=8YFLogxK

U2 - 10.1055/s-0038-1629854

DO - 10.1055/s-0038-1629854

M3 - 文章

C2 - 9467167

AN - SCOPUS:0031846080

SN - 0029-5566

VL - 37

SP - 23

EP - 25

JO - NuklearMedizin

JF - NuklearMedizin

IS - 1

ER -

Stunning effects after a diagnostic dose of Iodine-131

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this