Successful lysis of right and left heart thrombus by tissue plasminogen activator

Kuan Hung Yeh; Kuo Chun Hung; Fun Chung Lin; San Jou Yeh; Delon Wu

doi:10.1002/(SICI)1522-726X(200001)49:1<91::AID-CCD22>3.0.CO;2-B

Successful lysis of right and left heart thrombus by tissue plasminogen activator

Kuan Hung Yeh, Kuo Chun Hung, Fun Chung Lin, San Jou Yeh, Delon Wu^*

^*Corresponding author for this work

School of Medicine

Chang Gung University

Research output: Contribution to journal › Journal Article › peer-review

11 Scopus citations

Abstract

Tissue plasminogen activator (t-PA) was administered to three patients with newly developed intracardiac thrombi. Cases 1 and 2 developed right heart thrombi after radiofrequency ablation for atrioventricular nodal reentrant tachycardia and case 3 had tachycardia-related cardiomyopathy and a left ventricular thrombus. In all three patients, the intracardiac thrombi were successfully eliminated following t-PA therapy without major bleeding complications. These observations suggest that t-PA is effective in lysing new thrombus complicating radiofrequency ablation or heart failure and may be the therapy of choice in these conditions.

Original language	English
Pages (from-to)	91-96
Number of pages	6
Journal	Catheterization and Cardiovascular Interventions
Volume	49
Issue number	1
DOIs	https://doi.org/10.1002/(SICI)1522-726X(200001)49:1<91::AID-CCD22>3.0.CO;2-B
State	Published - 2000

Keywords

Catheter ablation
Tachycardia
Thrombolysis

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10.1002/(SICI)1522-726X(200001)49:1<91::AID-CCD22>3.0.CO;2-B

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title = "Successful lysis of right and left heart thrombus by tissue plasminogen activator",

abstract = "Tissue plasminogen activator (t-PA) was administered to three patients with newly developed intracardiac thrombi. Cases 1 and 2 developed right heart thrombi after radiofrequency ablation for atrioventricular nodal reentrant tachycardia and case 3 had tachycardia-related cardiomyopathy and a left ventricular thrombus. In all three patients, the intracardiac thrombi were successfully eliminated following t-PA therapy without major bleeding complications. These observations suggest that t-PA is effective in lysing new thrombus complicating radiofrequency ablation or heart failure and may be the therapy of choice in these conditions.",

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author = "Yeh, {Kuan Hung} and Hung, {Kuo Chun} and Lin, {Fun Chung} and Yeh, {San Jou} and Delon Wu",

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AU - Yeh, Kuan Hung

AU - Hung, Kuo Chun

AU - Lin, Fun Chung

AU - Yeh, San Jou

AU - Wu, Delon

PY - 2000

Y1 - 2000

N2 - Tissue plasminogen activator (t-PA) was administered to three patients with newly developed intracardiac thrombi. Cases 1 and 2 developed right heart thrombi after radiofrequency ablation for atrioventricular nodal reentrant tachycardia and case 3 had tachycardia-related cardiomyopathy and a left ventricular thrombus. In all three patients, the intracardiac thrombi were successfully eliminated following t-PA therapy without major bleeding complications. These observations suggest that t-PA is effective in lysing new thrombus complicating radiofrequency ablation or heart failure and may be the therapy of choice in these conditions.

AB - Tissue plasminogen activator (t-PA) was administered to three patients with newly developed intracardiac thrombi. Cases 1 and 2 developed right heart thrombi after radiofrequency ablation for atrioventricular nodal reentrant tachycardia and case 3 had tachycardia-related cardiomyopathy and a left ventricular thrombus. In all three patients, the intracardiac thrombi were successfully eliminated following t-PA therapy without major bleeding complications. These observations suggest that t-PA is effective in lysing new thrombus complicating radiofrequency ablation or heart failure and may be the therapy of choice in these conditions.

KW - Catheter ablation

KW - Tachycardia

KW - Thrombolysis

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M3 - 文章

C2 - 10627378

AN - SCOPUS:0033988770

SN - 1522-1946

VL - 49

SP - 91

EP - 96

JO - Catheterization and Cardiovascular Interventions

JF - Catheterization and Cardiovascular Interventions

IS - 1

ER -

Successful lysis of right and left heart thrombus by tissue plasminogen activator

Abstract

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