Abstract
In the present study, we describe unrelated umbilical cord blood transplantation (CBT) in a 7-year-old Taiwanese boy with atypical chronic myeloid leukemia (BCR-ABL 1 negative). Physical examination was notable for splenomegaly. Cytogenetic analyses from the bone marrow revealed a t(3;5)(p21;q31) translocation. The patient then underwent CBT from an HLA-mismatched (two loci by serotype, three loci by genotype) unrelated donor of Caucasian origin. Times to neutrophil and platelet engraftment were 21 and 62 days post-transplant, respectively. Acute graft-versus-host disease following transplantation was minimal. The patient remains in continuing hematological remission with full donor chimerism 28 months after transplantation.
Original language | English |
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Pages (from-to) | 144-146 |
Number of pages | 3 |
Journal | International Journal of Hematology |
Volume | 97 |
Issue number | 1 |
DOIs | |
State | Published - 01 2013 |
Keywords
- Atypical chronic myeloid leukemia
- Cytogenetic analyses
- Unrelated cord blood transplantation