18F-FDG PET/CT in detection of gynecomastia in patients with hepatocellular carcinoma

Hsin Yi Wang, Long Bin Jeng, Ming Chia Lin, Chih Hao Chao, Wan Yu Lin, Chia Hung Kao*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

7 Scopus citations

Abstract

Objective: We retrospectively investigate the prevalence of gynecomastia as false-positive 2-[18F]fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging in patients with hepatocellular carcinoma (HCC). Methods: Among the 127 male HCC patients who underwent 18F-FDG PET/CT scan, the 18FDG uptakes at the bilateral breasts in 9 patients with gynecomastia were recorded as standard uptake value (SUVmax) and the visual interpretation in both early and delayed images. Results: The mean early SUVmax was 1.58/1.57 (right/left breast) in nine gynecomastia patients. The three patients with early visual score of 3 had higher early SUVmaxs. Conclusion: Gynecomastia is a possible cause of false-positive uptake on 18F-FDG PET/CT images.

Original languageEnglish
Pages (from-to)942-946
Number of pages5
JournalClinical Imaging
Volume37
Issue number5
DOIs
StatePublished - 09 2013
Externally publishedYes

Keywords

  • FDG PET/CT
  • Gynecomastia
  • Hepatocellular carcinoma
  • SUVmax

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