TY - JOUR
T1 - Surgical outcome evaluation of perforated gastric cancer
T2 - from the aspects of both acute care surgery and surgical oncology
AU - Wang, Shang Yu
AU - Hsu, Chih Ho
AU - Liao, Chien Hung
AU - Fu, Chih Yuan
AU - Ouyang, Chun Hsiang
AU - Cheng, Chi Tung
AU - Hsu, Jun Te
AU - Yeh, Ta Sen
AU - Yeh, Chun Nan
N1 - Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/12/2
Y1 - 2017/12/2
N2 - Background: Perforated gastric cancer (PGC) is a rare condition of gastric cancer (GC). In this study, we sought to assess the outcome of PGC from the aspects of both acute care surgery and surgical oncology at a single institute, Chang Gung Memorial Hospital (CGMH). Methods: From 1997 to 2013, 6864 patients were diagnosed with GC and 2738 were diagnosed with gastroduodenal perforation at CGMH. In total, 29 patients with PGC were identified. Immediate surgical and long-term oncologic outcomes were evaluated after an appropriate matching process was performed. Results: The immediate surgical outcome of PGC, i.e., the hospital mortality rate within 30 d after surgery, did not significantly differ from that of non-cancer related gastroduodenal perforation. The long-term oncologic outcome, with matching by age, gender, year of surgery and AJCC 7th stage grouping, also did not significantly differ from that of GC without perforation. Conclusions: Aggressive surgical treatment, including an initial emergency procedure for containing peritonitis and radical surgery for GC, may benefit PGC patients in terms of both the immediate and oncologic outcomes.
AB - Background: Perforated gastric cancer (PGC) is a rare condition of gastric cancer (GC). In this study, we sought to assess the outcome of PGC from the aspects of both acute care surgery and surgical oncology at a single institute, Chang Gung Memorial Hospital (CGMH). Methods: From 1997 to 2013, 6864 patients were diagnosed with GC and 2738 were diagnosed with gastroduodenal perforation at CGMH. In total, 29 patients with PGC were identified. Immediate surgical and long-term oncologic outcomes were evaluated after an appropriate matching process was performed. Results: The immediate surgical outcome of PGC, i.e., the hospital mortality rate within 30 d after surgery, did not significantly differ from that of non-cancer related gastroduodenal perforation. The long-term oncologic outcome, with matching by age, gender, year of surgery and AJCC 7th stage grouping, also did not significantly differ from that of GC without perforation. Conclusions: Aggressive surgical treatment, including an initial emergency procedure for containing peritonitis and radical surgery for GC, may benefit PGC patients in terms of both the immediate and oncologic outcomes.
KW - PPU
KW - Perforated gastric cancer
KW - acute care surgery
KW - gastric adenocarcinoma
KW - perforated peptic ulcer
UR - http://www.scopus.com/inward/record.url?scp=85028566084&partnerID=8YFLogxK
U2 - 10.1080/00365521.2017.1369562
DO - 10.1080/00365521.2017.1369562
M3 - 文章
C2 - 28838270
AN - SCOPUS:85028566084
SN - 0036-5521
VL - 52
SP - 1371
EP - 1376
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
IS - 12
ER -