Synthesis and characterization of novel block copolymer from trans-4-hydroxy-L-proline and poly(ethylene glycol)

Ren Shen Lee; Jen Ming Yang

doi:10.1002/app.1588

Synthesis and characterization of novel block copolymer from trans-4-hydroxy-L-proline and poly(ethylene glycol)

Ren Shen Lee^*, Jen Ming Yang

^*Corresponding author for this work

Chang Gung University

Research output: Contribution to journal › Journal Article › peer-review

8 Scopus citations

Abstract

A series of novel ABA-type block copolymers were synthesized by polymerization of trans-4-hydroxy-L-proline (HyP) in the presence of various molecular weight poly(ethylene glycol)s (PEGs), a bifunctional OH-terminated PEG using stannous octoate as catalyst. The optimal reaction conditions for the synthesis of the copolymers were obtained with 5 wt% stannous octoate at 140°C under vacuum (20 mmHg) for 24 h. The synthesized copolymers were characterized by IR spectroohotometry, proton nuclear magnetic resonance, differential scanning calorimetry, and Ubbelohde viscometer. The glass transition temperature (T_g) of the copolymers shifted to significantly higher temperature with increasing the number average degree of polymerization and HyP/PEO molar ratio. In contrast, the melting temperature (T_m) decreased with increasing the HyP/PEO molar ratio.

Original language	English
Pages (from-to)	1581-1587
Number of pages	7
Journal	Journal of Applied Polymer Science
Volume	81
Issue number	7
DOIs	https://doi.org/10.1002/app.1588
State	Published - 15 08 2001
Externally published	Yes

Keywords

Poly(HyP-co-PEG)
Poly(ethylene glycol)
Pseudohydroxyproline

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10.1002/app.1588

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title = "Synthesis and characterization of novel block copolymer from trans-4-hydroxy-L-proline and poly(ethylene glycol)",

abstract = "A series of novel ABA-type block copolymers were synthesized by polymerization of trans-4-hydroxy-L-proline (HyP) in the presence of various molecular weight poly(ethylene glycol)s (PEGs), a bifunctional OH-terminated PEG using stannous octoate as catalyst. The optimal reaction conditions for the synthesis of the copolymers were obtained with 5 wt% stannous octoate at 140°C under vacuum (20 mmHg) for 24 h. The synthesized copolymers were characterized by IR spectroohotometry, proton nuclear magnetic resonance, differential scanning calorimetry, and Ubbelohde viscometer. The glass transition temperature (Tg) of the copolymers shifted to significantly higher temperature with increasing the number average degree of polymerization and HyP/PEO molar ratio. In contrast, the melting temperature (Tm) decreased with increasing the HyP/PEO molar ratio.",

keywords = "Poly(HyP-co-PEG), Poly(ethylene glycol), Pseudohydroxyproline",

author = "Lee, {Ren Shen} and Yang, {Jen Ming}",

year = "2001",

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doi = "10.1002/app.1588",

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T1 - Synthesis and characterization of novel block copolymer from trans-4-hydroxy-L-proline and poly(ethylene glycol)

AU - Lee, Ren Shen

AU - Yang, Jen Ming

PY - 2001/8/15

Y1 - 2001/8/15

N2 - A series of novel ABA-type block copolymers were synthesized by polymerization of trans-4-hydroxy-L-proline (HyP) in the presence of various molecular weight poly(ethylene glycol)s (PEGs), a bifunctional OH-terminated PEG using stannous octoate as catalyst. The optimal reaction conditions for the synthesis of the copolymers were obtained with 5 wt% stannous octoate at 140°C under vacuum (20 mmHg) for 24 h. The synthesized copolymers were characterized by IR spectroohotometry, proton nuclear magnetic resonance, differential scanning calorimetry, and Ubbelohde viscometer. The glass transition temperature (Tg) of the copolymers shifted to significantly higher temperature with increasing the number average degree of polymerization and HyP/PEO molar ratio. In contrast, the melting temperature (Tm) decreased with increasing the HyP/PEO molar ratio.

AB - A series of novel ABA-type block copolymers were synthesized by polymerization of trans-4-hydroxy-L-proline (HyP) in the presence of various molecular weight poly(ethylene glycol)s (PEGs), a bifunctional OH-terminated PEG using stannous octoate as catalyst. The optimal reaction conditions for the synthesis of the copolymers were obtained with 5 wt% stannous octoate at 140°C under vacuum (20 mmHg) for 24 h. The synthesized copolymers were characterized by IR spectroohotometry, proton nuclear magnetic resonance, differential scanning calorimetry, and Ubbelohde viscometer. The glass transition temperature (Tg) of the copolymers shifted to significantly higher temperature with increasing the number average degree of polymerization and HyP/PEO molar ratio. In contrast, the melting temperature (Tm) decreased with increasing the HyP/PEO molar ratio.

KW - Poly(HyP-co-PEG)

KW - Poly(ethylene glycol)

KW - Pseudohydroxyproline

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U2 - 10.1002/app.1588

DO - 10.1002/app.1588

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JO - Journal of Applied Polymer Science

JF - Journal of Applied Polymer Science

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ER -

Synthesis and characterization of novel block copolymer from trans-4-hydroxy-L-proline and poly(ethylene glycol)

Abstract

Keywords

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