Synthesis, characterization, and antibacterial activity of silver-doped silica nanocomposite particles

Guo Shu Chen, Chun Nan Chen, Tzu Tsung Tseng, Ming Hsiung Wei, J. H. Hsieh, Wenjea J. Tseng*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

19 Scopus citations


Silver nanoparticles were adsorbed preferentially on silica surface to form composite particles using a reverse micelle process that stabilizes the silver particles by an anionic sodium bis(2-ethylhexyl) sulfosuccinate (AOT) surfactant in isooctane solvent together with the silica particles in which their surface being mediated by a cationic poly(allylamine hydrochloride) (PAH) polyelectrolyte. The heterogeneous adsorption was rendered by both electrostatic attraction and hydrophilic/hydrophobic interaction, and was carried out in multiple deposition cycles. The resulting nanocomposite particles were characterized by zeta-potential measurement, electron microscopy, X-ray diffractometry, field-emission electron spectroscopy for chemical analysis (ESCA), and inductively coupled plasma analysis, respectively. In addition, antibacterial activity of the composite particles was examined against Escherichia coli (E. coli) in aqueous environment.

Original languageEnglish
Pages (from-to)90-97
Number of pages8
JournalJournal of Nanoscience and Nanotechnology
Issue number1
StatePublished - 01 2011
Externally publishedYes


  • Antibacterial activity
  • Composite
  • Silica
  • Silver


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