Taiwan ocular inflammation society consensus recommendations for the management of juvenile idiopathic arthritis-associated uveitis

Wei Dar Chen, Cheng Hsiu Wu, Po Yi Wu, Chang Ping Lin, Liang Shiou Ou, De Kuang Hwang, Shwu Jiuan Sheu, Wei Yu Chiang, Yo Chen Chang, Chun Ju Lin, Wei Chun Chan, Yueh Fu Fang, Jerry Chien-Chieh Huang, Tzu En Kao, Fang Yi Chiu, Ning Yi Hsia, Yih Shiou Hwang*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

We presented the development of a consensus guideline for managing juvenile idiopathic arthritis-associated uveitis (JIAU) in Taiwan, considering regional differences in manifestation and epidemiology. The Taiwan Ocular Inflammation Society (TOIS) committee formulated this guideline using a modified Delphi approach with two panel meetings. Recommendations were based on a comprehensive evidence-based literature review and expert clinical experiences, and were graded according to the Oxford Centre for Evidence-Based Medicine's “Levels of Evidence” guideline (March 2009). The TOIS consensus guideline consists of 10 recommendations in four categories: screening and diagnosis, treatment, complications, and monitoring, covering a total of 27 items. These recommendations received over 75% agreement from the panelists. Early diagnosis and a coordinated referral system between ophthalmologists and pediatric rheumatologists are crucial to prevent irreversible visual impairment in children with JIAU. However, achieving a balance between disease activity and medication use remains a key challenge in JIAU management, necessitating further clinical studies.

Original languageEnglish
JournalJournal of the Formosan Medical Association
Early online date28 02 2024
DOIs
StateE-pub ahead of print - 28 02 2024
Externally publishedYes

Bibliographical note

Copyright © 2024 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.

Keywords

  • Anti-tumor necrosis factor
  • DMARDs
  • Juvenile idiopathic arthritis-associated uveitis
  • Methotrexate
  • Taiwan

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