Tertiary prevention of hcc in chronic hepatitis b or c infected patients

Wei Teng; Yen Chun Liu; Wen Juei Jeng; Chien Wei Su

doi:10.3390/cancers13071729

Tertiary prevention of hcc in chronic hepatitis b or c infected patients

Wei Teng, Yen Chun Liu, Wen Juei Jeng^*, Chien Wei Su^*

^*Corresponding author for this work

School of Medicine

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

Hepatocellular carcinoma (HCC) ranks as a leading cause of common cancer and cancer-related death. The major etiology of HCC is due to chronic hepatitis virus including HBV and HCV infections. Scheduled HCC surveillance in high risk populations improves the early detection rate and the feasibility of curative treatment. However, high HCC recurrence rate still accounts for the poor prognosis of HCC patients. In this article, we critically review the pathogenesis of viral hepatitis-related hepatocellular carcinoma and the evidence of tertiary prevention efficacy by current available antiviral treatment, and discuss the knowledge gap in viral hepatitis-related HCC tertiary prevention.

Original language	English
Article number	1729
Journal	Cancers
Volume	13
Issue number	7
DOIs	https://doi.org/10.3390/cancers13071729
State	Published - 01 04 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

Carcinogenesis
Cirrhosis
Direct acting antiviral agents
Interferon
Nucleos(t)ide ana-logues
Sustained virologic response

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3390/cancers13071729

Cite this

@article{9397cf35598e4fcaad88297762b44da2,

title = "Tertiary prevention of hcc in chronic hepatitis b or c infected patients",

abstract = "Hepatocellular carcinoma (HCC) ranks as a leading cause of common cancer and cancer-related death. The major etiology of HCC is due to chronic hepatitis virus including HBV and HCV infections. Scheduled HCC surveillance in high risk populations improves the early detection rate and the feasibility of curative treatment. However, high HCC recurrence rate still accounts for the poor prognosis of HCC patients. In this article, we critically review the pathogenesis of viral hepatitis-related hepatocellular carcinoma and the evidence of tertiary prevention efficacy by current available antiviral treatment, and discuss the knowledge gap in viral hepatitis-related HCC tertiary prevention.",

keywords = "Carcinogenesis, Cirrhosis, Direct acting antiviral agents, Interferon, Nucleos(t)ide ana-logues, Sustained virologic response",

author = "Wei Teng and Liu, {Yen Chun} and Jeng, {Wen Juei} and Su, {Chien Wei}",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = apr,

day = "1",

doi = "10.3390/cancers13071729",

language = "英语",

volume = "13",

journal = "Cancers",

issn = "2072-6694",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "7",

}

TY - JOUR

T1 - Tertiary prevention of hcc in chronic hepatitis b or c infected patients

AU - Teng, Wei

AU - Liu, Yen Chun

AU - Jeng, Wen Juei

AU - Su, Chien Wei

PY - 2021/4/1

Y1 - 2021/4/1

N2 - Hepatocellular carcinoma (HCC) ranks as a leading cause of common cancer and cancer-related death. The major etiology of HCC is due to chronic hepatitis virus including HBV and HCV infections. Scheduled HCC surveillance in high risk populations improves the early detection rate and the feasibility of curative treatment. However, high HCC recurrence rate still accounts for the poor prognosis of HCC patients. In this article, we critically review the pathogenesis of viral hepatitis-related hepatocellular carcinoma and the evidence of tertiary prevention efficacy by current available antiviral treatment, and discuss the knowledge gap in viral hepatitis-related HCC tertiary prevention.

AB - Hepatocellular carcinoma (HCC) ranks as a leading cause of common cancer and cancer-related death. The major etiology of HCC is due to chronic hepatitis virus including HBV and HCV infections. Scheduled HCC surveillance in high risk populations improves the early detection rate and the feasibility of curative treatment. However, high HCC recurrence rate still accounts for the poor prognosis of HCC patients. In this article, we critically review the pathogenesis of viral hepatitis-related hepatocellular carcinoma and the evidence of tertiary prevention efficacy by current available antiviral treatment, and discuss the knowledge gap in viral hepatitis-related HCC tertiary prevention.

KW - Carcinogenesis

KW - Cirrhosis

KW - Direct acting antiviral agents

KW - Interferon

KW - Nucleos(t)ide ana-logues

KW - Sustained virologic response

UR - http://www.scopus.com/inward/record.url?scp=85103560954&partnerID=8YFLogxK

U2 - 10.3390/cancers13071729

DO - 10.3390/cancers13071729

M3 - 文献综述

AN - SCOPUS:85103560954

SN - 2072-6694

VL - 13

JO - Cancers

JF - Cancers

IS - 7

M1 - 1729

ER -

Tertiary prevention of hcc in chronic hepatitis b or c infected patients

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this