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The Bridging Effect of Artificial Dermis on Reconstruction of Skin Avulsion Injury

  • Yun Nan Lin*
  • , Yu Chi Wang
  • , Su Shin Lee
  • , Meng Chien Willie Hsieh
  • , Sin Daw Lin
  • , Shu Hung Huang
  • , Tsai Ming Lin
  • , Yur Ren Kuo
  • *Corresponding author for this work
  • Kaohsiung Medical University
  • Kaohsiung Municipal Ta-Tung Hospital
  • Charming Institute of Aesthetic and Regenerative Surgery (CIARS)

Research output: Contribution to journalJournal Article peer-review

4 Scopus citations

Abstract

Skin avulsion wounds are expected to be swollen and tense after trauma, and skin perfusion can be compromised after primary closure, resulting in wound dehiscence and poor healing. The artificial dermis (AD) serves as a dermal regeneration template that is used to heal skin defects with secondary intention. Therefore, the aim of this study is to evaluate the effect of AD application on traumatic skin avulsion injuries compared to conventional primary closure. A retrospective cohort of 20 patients with skin avulsion injuries were included the study: ten patients were treated with AD and ten patients were managed with primary closure. When compared to the primary closure group, AD group had a shorter average healing time (58.40 ± 26.94 days V 65.50 ± 46.45 days) and significantly higher flap viability (92.00 ± 13.17% V 78.00 ± 13.98%; p = .03). In conclusion, AD is a promising material for the treatment of skin avulsion injury and produces better clinical results.

Original languageEnglish
Pages (from-to)15347346231158175
Number of pages8
JournalInternational Journal of Lower Extremity Wounds
Volume24
Issue number4
Early online date22 02 2023
DOIs
StateE-pub ahead of print - 22 02 2023
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2023

Keywords

  • artificial dermis
  • flap viability
  • primary closure
  • skin avulsion
  • wound healing

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