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The emerging role of IL-15 in NK-cell development

  • Chau Ching Liu*
  • , Bice Perussia
  • , John Ding E. Young
  • *Corresponding author for this work
  • University of Pittsburgh
  • Thomas Jefferson University
  • Rockefeller University

Research output: Contribution to journal › Short survey › peer-review

80 Scopus citations

Abstract

Natural killer (NK) and T cells appear to have a common progenitor cell. Interleukin 15 (IL-15) plays an important role in directing such progenitors to commit to NK-cell differentiation. Several other cytokines such as Flt-3 ligand and IL-7 appear to modulate or enhance the effects of IL-15.

Original languageEnglish
Pages (from-to)113-116
Number of pages4
JournalImmunology Today
Volume21
Issue number3
DOIs
StatePublished - 01 03 2000
Externally publishedYes

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