The expression of DAZL1 in the ovary of the human female fetus

Meng Yin Tsai; Shiuh Young Chang; Hsin Yi Lo; I. Hsuan Chen; Fu Jeng Huang; Fu Tsai Kung; Ying Jen Lu

doi:10.1016/S0015-0282(99)00544-0

The expression of DAZL1 in the ovary of the human female fetus

Meng Yin Tsai^*, Shiuh Young Chang, Hsin Yi Lo, I. Hsuan Chen, Fu Jeng Huang, Fu Tsai Kung, Ying Jen Lu

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

19 Scopus citations

Abstract

Objective: To determine whether DAZL1 is expressed in human fetal ovarian tissue. Design: The presence of DAZL1 expression was determined by reverse transcriptase polymerase chain reaction (RT-PCR). Setting: Academic tertiary care medical center and research unit of university. Patient(s): Five female abortuses between the 19th and 22nd week of gestational age. Intervention(s): Fetal ovarian tissues were collected immediately after the cessation of the heart beat. Main Outcome Measure(s): The product of RT-PCR. Result(s): DAZL1 expression was detected in all five samples. Conclusion(s): DAZL1 is not only expressed in human testes but also in ovaries. It may play a role in germ cell survival and gonad development in both sexes.

Original language	English
Pages (from-to)	627-630
Number of pages	4
Journal	Fertility and Sterility
Volume	73
Issue number	3
DOIs	https://doi.org/10.1016/S0015-0282(99)00544-0
State	Published - 03 2000
Externally published	Yes

Keywords

DAZL1
Fetus
Ovary
Reverse transcriptase polymerase chain reaction (RT- PCR)

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10.1016/S0015-0282(99)00544-0

Cite this

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title = "The expression of DAZL1 in the ovary of the human female fetus",

abstract = "Objective: To determine whether DAZL1 is expressed in human fetal ovarian tissue. Design: The presence of DAZL1 expression was determined by reverse transcriptase polymerase chain reaction (RT-PCR). Setting: Academic tertiary care medical center and research unit of university. Patient(s): Five female abortuses between the 19th and 22nd week of gestational age. Intervention(s): Fetal ovarian tissues were collected immediately after the cessation of the heart beat. Main Outcome Measure(s): The product of RT-PCR. Result(s): DAZL1 expression was detected in all five samples. Conclusion(s): DAZL1 is not only expressed in human testes but also in ovaries. It may play a role in germ cell survival and gonad development in both sexes.",

keywords = "DAZL1, Fetus, Ovary, Reverse transcriptase polymerase chain reaction (RT- PCR)",

author = "Tsai, {Meng Yin} and Chang, {Shiuh Young} and Lo, {Hsin Yi} and Chen, {I. Hsuan} and Huang, {Fu Jeng} and Kung, {Fu Tsai} and Lu, {Ying Jen}",

year = "2000",

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doi = "10.1016/S0015-0282(99)00544-0",

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volume = "73",

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T1 - The expression of DAZL1 in the ovary of the human female fetus

AU - Tsai, Meng Yin

AU - Chang, Shiuh Young

AU - Lo, Hsin Yi

AU - Chen, I. Hsuan

AU - Huang, Fu Jeng

AU - Kung, Fu Tsai

AU - Lu, Ying Jen

PY - 2000/3

Y1 - 2000/3

N2 - Objective: To determine whether DAZL1 is expressed in human fetal ovarian tissue. Design: The presence of DAZL1 expression was determined by reverse transcriptase polymerase chain reaction (RT-PCR). Setting: Academic tertiary care medical center and research unit of university. Patient(s): Five female abortuses between the 19th and 22nd week of gestational age. Intervention(s): Fetal ovarian tissues were collected immediately after the cessation of the heart beat. Main Outcome Measure(s): The product of RT-PCR. Result(s): DAZL1 expression was detected in all five samples. Conclusion(s): DAZL1 is not only expressed in human testes but also in ovaries. It may play a role in germ cell survival and gonad development in both sexes.

AB - Objective: To determine whether DAZL1 is expressed in human fetal ovarian tissue. Design: The presence of DAZL1 expression was determined by reverse transcriptase polymerase chain reaction (RT-PCR). Setting: Academic tertiary care medical center and research unit of university. Patient(s): Five female abortuses between the 19th and 22nd week of gestational age. Intervention(s): Fetal ovarian tissues were collected immediately after the cessation of the heart beat. Main Outcome Measure(s): The product of RT-PCR. Result(s): DAZL1 expression was detected in all five samples. Conclusion(s): DAZL1 is not only expressed in human testes but also in ovaries. It may play a role in germ cell survival and gonad development in both sexes.

KW - DAZL1

KW - Fetus

KW - Ovary

KW - Reverse transcriptase polymerase chain reaction (RT- PCR)

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The expression of DAZL1 in the ovary of the human female fetus

Abstract

Keywords

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