The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: An analysis of 618 individuals

Yu Lin Ko; Tsu Shiu Hsu; Shy Meeng Wu; Yu Shien Ko; Chi Jen Chang; Shu Mei Wang; Wei Jan Chen; Nye Jan Cheng; Chi Tai Kuo; Cheng-Wen Chiang; Ying Shiung Lee

doi:10.1007/s004390050184

The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: An analysis of 618 individuals

Yu Lin Ko^*, Tsu Shiu Hsu, Shy Meeng Wu, Yu Shien Ko, Chi Jen Chang, Shu Mei Wang, Wei Jan Chen, Nye Jan Cheng, Chi Tai Kuo, Cheng-Wen Chiang, Ying Shiung Lee

^*Corresponding author for this work

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

30 Scopus citations

Abstract

To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese.

Original language	English
Pages (from-to)	176-177
Number of pages	2
Journal	Human Genetics
Volume	98
Issue number	2
DOIs	https://doi.org/10.1007/s004390050184
State	Published - 1996
Externally published	Yes

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title = "The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: An analysis of 618 individuals",

abstract = "To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese.",

author = "Ko, {Yu Lin} and Hsu, {Tsu Shiu} and Wu, {Shy Meeng} and Ko, {Yu Shien} and Chang, {Chi Jen} and Wang, {Shu Mei} and Chen, {Wei Jan} and Cheng, {Nye Jan} and Kuo, {Chi Tai} and Cheng-Wen Chiang and Lee, {Ying Shiung}",

year = "1996",

doi = "10.1007/s004390050184",

language = "英语",

volume = "98",

pages = "176--177",

journal = "Human Genetics",

issn = "0340-6717",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "2",

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TY - JOUR

T1 - The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese

T2 - An analysis of 618 individuals

AU - Ko, Yu Lin

AU - Hsu, Tsu Shiu

AU - Wu, Shy Meeng

AU - Ko, Yu Shien

AU - Chang, Chi Jen

AU - Wang, Shu Mei

AU - Chen, Wei Jan

AU - Cheng, Nye Jan

AU - Kuo, Chi Tai

AU - Chiang, Cheng-Wen

AU - Lee, Ying Shiung

PY - 1996

Y1 - 1996

N2 - To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese.

AB - To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese.

UR - http://www.scopus.com/inward/record.url?scp=8944233872&partnerID=8YFLogxK

U2 - 10.1007/s004390050184

DO - 10.1007/s004390050184

M3 - 文章

C2 - 8698336

AN - SCOPUS:8944233872

SN - 0340-6717

VL - 98

SP - 176

EP - 177

JO - Human Genetics

JF - Human Genetics

IS - 2

ER -

The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: An analysis of 618 individuals

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