Abstract
Maternal nutrition plays a decisive role in developmental programming of many non-communicable diseases (NCDs). A variety of nutritional insults during gestation can cause programming and contribute to the development of adult-onset diseases. Nutritional interventions during pregnancy may serve as reprogramming strategies to reverse programming processes and prevent NCDs. In this review, firstly we summarize epidemiological evidence for nutritional programming of human disease. It will also discuss evidence from animal models, for the common mechanisms underlying nutritional programming, and potential nutritional interventions used as reprogramming strategies.
| Original language | English |
|---|---|
| Article number | 894 |
| Journal | Nutrients |
| Volume | 11 |
| Issue number | 4 |
| DOIs | |
| State | Published - 04 2019 |
Bibliographical note
Publisher Copyright:© 2019 by the authors. Licensee MDPI, Basel, Switzerland.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Developmental origins of health and disease (DOHaD)
- Gut microbiota
- Non-communicable disease
- Nutrient-sensing signal
- Nutrition
- Oxidative stress
- Pregnancy
- Reprogramming
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