The good, the bad, and the ugly of pregnancy nutrients and developmental programming of adult disease

Chien Ning Hsu; You Lin Tain

doi:10.3390/nu11040894

The good, the bad, and the ugly of pregnancy nutrients and developmental programming of adult disease

Chien Ning Hsu, You Lin Tain^*

^*Corresponding author for this work

School of Medicine

Research output: Contribution to journal › Review article › peer-review

85 Scopus citations

Abstract

Maternal nutrition plays a decisive role in developmental programming of many non-communicable diseases (NCDs). A variety of nutritional insults during gestation can cause programming and contribute to the development of adult-onset diseases. Nutritional interventions during pregnancy may serve as reprogramming strategies to reverse programming processes and prevent NCDs. In this review, firstly we summarize epidemiological evidence for nutritional programming of human disease. It will also discuss evidence from animal models, for the common mechanisms underlying nutritional programming, and potential nutritional interventions used as reprogramming strategies.

Original language	English
Article number	894
Journal	Nutrients
Volume	11
Issue number	4
DOIs	https://doi.org/10.3390/nu11040894
State	Published - 04 2019

Bibliographical note

Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

Developmental origins of health and disease (DOHaD)
Gut microbiota
Non-communicable disease
Nutrient-sensing signal
Nutrition
Oxidative stress
Pregnancy
Reprogramming

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/nu11040894

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title = "The good, the bad, and the ugly of pregnancy nutrients and developmental programming of adult disease",

abstract = "Maternal nutrition plays a decisive role in developmental programming of many non-communicable diseases (NCDs). A variety of nutritional insults during gestation can cause programming and contribute to the development of adult-onset diseases. Nutritional interventions during pregnancy may serve as reprogramming strategies to reverse programming processes and prevent NCDs. In this review, firstly we summarize epidemiological evidence for nutritional programming of human disease. It will also discuss evidence from animal models, for the common mechanisms underlying nutritional programming, and potential nutritional interventions used as reprogramming strategies.",

keywords = "Developmental origins of health and disease (DOHaD), Gut microbiota, Non-communicable disease, Nutrient-sensing signal, Nutrition, Oxidative stress, Pregnancy, Reprogramming",

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AU - Tain, You Lin

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AB - Maternal nutrition plays a decisive role in developmental programming of many non-communicable diseases (NCDs). A variety of nutritional insults during gestation can cause programming and contribute to the development of adult-onset diseases. Nutritional interventions during pregnancy may serve as reprogramming strategies to reverse programming processes and prevent NCDs. In this review, firstly we summarize epidemiological evidence for nutritional programming of human disease. It will also discuss evidence from animal models, for the common mechanisms underlying nutritional programming, and potential nutritional interventions used as reprogramming strategies.

KW - Developmental origins of health and disease (DOHaD)

KW - Gut microbiota

KW - Non-communicable disease

KW - Nutrient-sensing signal

KW - Nutrition

KW - Oxidative stress

KW - Pregnancy

KW - Reprogramming

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SN - 2072-6643

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JF - Nutrients

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M1 - 894

ER -

The good, the bad, and the ugly of pregnancy nutrients and developmental programming of adult disease

Abstract

Bibliographical note

Keywords

UN SDGs

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