Abstract
The development of a specific, reliable and noninvasive method for measuring oxidative stress in humans is essential for establishing the role of free radicals in human diseases. Currently, accurate techniques to assess oxidant injury in vivo are extremely limited although a number of approaches are being investigated. Of these, the measurement of specific products of nonenzymatic lipid peroxidation, the F2-isoprostanes (F2-IsoPs), appears to be a more accurate marker of oxidative stress in vivo in humans than other available methods. The purpose of this brief review is to acquaint the reader with the IsoPs from a biochemical perspective and to provide information regarding the utility of quantifying these compounds as indicators of oxidant stress.
| Original language | English |
|---|---|
| Pages (from-to) | 415-420 |
| Number of pages | 6 |
| Journal | Journal of Biomedical Science |
| Volume | 5 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1998 |
| Externally published | Yes |
Keywords
- Gas chromatography
- Human disease
- Isoprostanes
- Lipid peroxidation
- Mass spectrometry
- Oxidative stress
Fingerprint
Dive into the research topics of 'The isoprostanes: Unique bioactive products of lipid peroxidation: An overview'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver