The lorazepam and diazepam protocol for catatonia due to general medical condition and substance in Liaison psychiatry

Chin Chuen Lin, Yi Yung Hung, Meng Chang Tsai, Tiao Lai Huang

Research output: Contribution to journalJournal Article peer-review

18 Scopus citations

Abstract

Objective: The lorazepam-diazepam protocol had been proved to rapidly and effectively relieve catatonia in patients with schizophrenia or mood disorder. This study aims to investigate the efficacy of lorazepam-diazepam protocol in catatonia due to general medical conditions (GMC) and substance. Method: Patients with catatonia that required psychiatric intervention in various settings of a medical center were included. The lorazepam-diazepam protocol had been used to treat the catatonia due to GMC or substance according to DSM-IVcriteria. The treatment response had been assessed by two psychiatrists. Results: Eighteen (85.7%) of 21 catatonic patients due to GMC or substance became free of catatonia after the lorazepam-diazepam protocol. Five (23.8%) of the 21 patients had passed away with various causes of death and wide range of time periods after catatonia. Conclusion: Our results showed that the lorazepam-diazepam protocol could rapidly and effectively relieve catatonia due to GMC and substance.

Original languageEnglish
Article numbere0170452
JournalPLoS ONE
Volume12
Issue number1
DOIs
StatePublished - 01 2017

Bibliographical note

Publisher Copyright:
© 2017 Lin et al.

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