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The macrophage

  • University of Oxford

Research output: Contribution to journalJournal Article peer-review

196 Scopus citations

Abstract

The macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied repertoire of plasma membrane and secretory molecules. Upon isolation from the body it continues to express special, as well as general, features of cellular organisation and function, which make it a delight to study in cell culture.

Original languageEnglish
Pages (from-to)977-986
Number of pages10
JournalBioEssays
Volume17
Issue number11
DOIs
StatePublished - 11 1995
Externally publishedYes

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