The microbicidal and cytoregulatory roles of NADPH oxidases

Hung Chi Yang, Mei Ling Cheng, Hung Yao Ho, Daniel Tsun-Yee Chiu*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

32 Scopus citations

Abstract

Despite their prominent microbicidal roles, NADPH oxidases (NOXs) have been recently found to regulate a wide variety of physiological activities. Through generation of reactive oxygen species (ROS), NOXs actively participate in cellular activities, including NET formation, inflammasome activation and wound sensing. The microbicidal and cytoregulatory roles of NOXs are contrasted in this review.

Original languageEnglish
Pages (from-to)109-120
Number of pages12
JournalMicrobes and Infection
Volume13
Issue number2
DOIs
StatePublished - 02 2011

Keywords

  • Dual oxidase
  • NADPH oxidase
  • Oxidative stress

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