Abstract
Despite their prominent microbicidal roles, NADPH oxidases (NOXs) have been recently found to regulate a wide variety of physiological activities. Through generation of reactive oxygen species (ROS), NOXs actively participate in cellular activities, including NET formation, inflammasome activation and wound sensing. The microbicidal and cytoregulatory roles of NOXs are contrasted in this review.
Original language | English |
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Pages (from-to) | 109-120 |
Number of pages | 12 |
Journal | Microbes and Infection |
Volume | 13 |
Issue number | 2 |
DOIs | |
State | Published - 02 2011 |
Keywords
- Dual oxidase
- NADPH oxidase
- Oxidative stress