The Prognostic Significance of SYNTAX Score After Early Percutaneous Transluminal Coronary Angioplasty for Acute ST Elevation Myocardial Infarction

Chia Hung Yang, Ming Jer Hsieh, Chun Chi Chen, Chao Yung Wang, Shang Hung Chang, Cheng Hung Lee, I. Chang Hsieh*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

12 Scopus citations

Abstract

Introduction: SYNergy between percutaneous coronary intervention (PCI) with TAXUS and Cardiac Surgery (SYNTAX) score, which is based on the characteristics of atherosclerotic lesions and the complexity of coronary artery anatomy, is useful for choosing an intervention strategy, but its prognostic significance for acute ST elevation of myocardial infarction (STEMI) remains unknown. This study aimed to redress this issue. Methods: Our observational study included 151 consecutive patients admitted for acute STEMI who underwent primary PCI between January 1, 2008 and December 31, 2009. The primary endpoint for analysis was 30-day cardiac death. Results: Among the 151 patients, cardiac death occurred in 10 (7%) within 30. days. After the first month, five patients died of non-cardiac causes, but no cardiac death occurred. Multivariate analysis showed that SYNTAX score (odds ratio [OR], 13.79, 95% confidence interval [CI], 1.24-153.38; p=0.033) and a symptom onset-to-therapy time interval >4. h (OR, 11.13; 95% CI, 1.08-114.42; p=0.043) were independent risk factors for 30-day mortality. The SYNTAX score cut-off for discriminating low and high risk was 22. Conclusions: SYNTAX score is an independent predictor of short-term cardiac mortality in patients with acute STEMI.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalHeart Lung and Circulation
Volume22
Issue number5
DOIs
StatePublished - 05 2013

Keywords

  • Acute ST elevation myocardial infarction
  • Cardiac death
  • SYNTAX score

Fingerprint

Dive into the research topics of 'The Prognostic Significance of SYNTAX Score After Early Percutaneous Transluminal Coronary Angioplasty for Acute ST Elevation Myocardial Infarction'. Together they form a unique fingerprint.

Cite this