The relationships of umbilical venous volume flow, birthweight and placental share in monochorionic twin pregnancies with and without selective intrauterine growth restriction

Yao Lung Chang*, Shuenn Dyh Chang, An Shine Chao, Chao Nin Wang, Tzu Hao Wang, Po Jen Cheng

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

17 Scopus citations

Abstract

This study was conducted to investigate the relationship among umbilical venous volume flow, birthweight and placental share in monochorionic twins with or without selective growth restriction. Having excluded cases complicated with twin-to-twin transfusion syndrome and one co-twin suffering intrauterine fetal death, a total of 51 monochorionic twin pregnancies were divided into two groups as with (group 1) and without (group 2) selective intrauterine growth restriction. Umbilical venous volume flow was calculated by multiplying the umbilical vein cross-sectional area by half of the maximal velocity around mid-trimester. The placentas were cut along the vascular equator into two individual placental masses. The discordance of birthweight was calculated as [(birthweight of larger twin - birthweight of smaller twin)/birthweight of larger twin x 100%]. The discordances of umbilical venous volume flow and placental share were calculated in a similar fashion. The median umbilical venous volume flow discordances (68.4% and 15.3% in groups 1 and 2 monochorionic twins, respectively) were similar and correlated well with the placental share discordances (66.6% and 18.5% in groups 1 and 2 monochorionic twins, respectively) but not with the birthweight discordance (28.6% and 6.4% in groups 1 and 2 monochorionic twins, respectively) in both groups. We concluded that the umbilical venous volume flow discordance reflects the placental share discordance rather than the birthweight discordance in monochorionic twin pregnancies.

Original languageEnglish
Pages (from-to)192-197
Number of pages6
JournalTwin Research and Human Genetics
Volume14
Issue number2
DOIs
StatePublished - 04 2011

Keywords

  • Intrauterine growth restriction
  • Monochorionic twin pregnancy
  • Placental share
  • Umbilical venous volume flow

Fingerprint

Dive into the research topics of 'The relationships of umbilical venous volume flow, birthweight and placental share in monochorionic twin pregnancies with and without selective intrauterine growth restriction'. Together they form a unique fingerprint.

Cite this