The role of mitochondria in the human ageing process

Y. H. Wei*, C. Y. Pang

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Ageing is a universal but complex biological process, characterised by an impairment of bioenergetic function, a decreased ability to respond to stress, and an increased risk of age-associated diseases. In this article, we review the role of mitochondria in the human ageing process from the point of view of the well-documented decline in respiratory function and the increase in mutation and oxidative damage to the mitochondrial DNA of ageing tissues.

Original languageEnglish
Pages (from-to)8-13
Number of pages6
JournalBio Tech International
Volume17
Issue number3
StatePublished - 06 2005
Externally publishedYes

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